- Tulobuterol
-
- $15.00
-
2021-07-13
- CAS:41570-61-0
- Min. Order: 1KG
- Purity: 99%+ HPLC
- Tulobuterol
-
- $15.00
-
2021-07-10
- CAS:41570-61-0
- Min. Order: 1KG
- Purity: 99%+ HPLC
- Tulobuterol
-
- $15.00
-
2021-07-02
- CAS:41570-61-0
- Min. Order: 1KG
- Purity: 99%+ HPLC
|
| | Tulobuterol Basic information |
| Product Name: | Tulobuterol | | Synonyms: | TULOBUTEROL;TULOBUTEROL BASE;Tulobuterol(baseandorunspecifiedsalt);alpha-[(tert-butylamino)methyl]-o-chlorobenzyl alcohol;2-Chloro-a-[[(1,1-dimethylethyl)amino]methyl]benzenemethano;Benzenemethanol, 2-chloro-a-[[(1,1-dimethylethyl)amino]methyl]- (9CI);HN 078;o-Chloro-a-[(tert-butylamino)methyl]benzyl alcohol | | CAS: | 41570-61-0 | | MF: | C12H18ClNO | | MW: | 227.73 | | EINECS: | | | Product Categories: | API;Amines;Aromatics;Intermediates & Fine Chemicals;Pharmaceuticals | | Mol File: | 41570-61-0.mol |  |
| | Tulobuterol Chemical Properties |
| Melting point | 89-91°C | | Boiling point | 338.2±27.0 °C(Predicted) | | density | 1.098±0.06 g/cm3(Predicted) | | RTECS | DA4734170 | | storage temp. | -20°C Freezer | | solubility | DMSO (Slightly), Methanol (Slightly) | | pka | 13.62±0.20(Predicted) | | form | Solid | | color | White to Off-White | | InChI | InChI=1S/C9H6F3IN2O2S/c1-18(16,17)15-8-3-6(9(10,11)12)5(4-14)2-7(8)13/h2-3,15H,1H3 | | InChIKey | YREYLAVBNPACJM-UHFFFAOYSA-N | | SMILES | Clc1c(cccc1)C(O)CNC(C)(C)C | | CAS DataBase Reference | 41570-61-0(CAS DataBase Reference) |
| Safety Statements | 24/25 | | HS Code | 29214990 | | Storage Class | 11 - Combustible Solids | | Toxicity | LD50 in male mice, rats, rabbits (mg/kg): 305, 850, 563 orally; 170, 417, 164 s.c. (Kubo, 1975) |
| | Tulobuterol Usage And Synthesis |
| Chemical Properties | Crystalline Solid | | Uses | Tulobuterol is a sympathomimetic drug used as a transdermal patch, increases normal diaphragm muscle strength. | | Uses | A sympathomimetic drug used as a transdermal patch, increases normal diaphragm muscle strength. A β-adrenergic receptor agonist, related structurally to Terbutaline (T109750). | | Uses | A adrenergic receptor agonist, related structurally to Terbutaline | | Definition | ChEBI: 2-(tert-butylamino)-1-(2-chlorophenyl)ethanol is an organochlorine compound. | | in vivo | In vivo effect of Tulobuterol is examined the on the contractility of diaphragm muscles prepared from mice (BALBs/c mice; 21.7 ± 0.2 g) treated with Endotoxin. Contractile parameters of force-frequency curves and twitch kinetics using untreated or treated diaphragm muscles at 0 (E0) and 4 (E4) hours after E. coli endotoxin (20 mg/kg) administration are measured. E0 and E4 diaphragm muscles are analyzed at 0, 12, and 24 h after transdermal Tulobuterol treatment. The force-frequency curves of E0 and E4 diaphragm muscles at three time points are not significantly changed each other, indicating that Tulobuterol patch restores the muscle contractility. Thus, diaphragm muscle contractility is maintained during 4 h of endotoxin administration with Tulobuterol patch for over 24 h[2]. | | IC 50 | β adrenergic receptor |
| | Tulobuterol Preparation Products And Raw materials |
|