Asthma drugs

Antiasthmatics are a class of drugs that can alleviate or terminate asthma attacks. Common antiasthmatics include:

  1. adrenomimetic drugs, the drugs that can increase intracellular cAMP concentration mainly through activating β-adrenergic receptor activation adenylate cyclase, and inhibit mastocytes from releasing allergenic substances, as well as relax the smooth muscle and dilate the bronchial tube, including epinephrine, ephedrine, isoproterenol, salbutamol and so on
  2. M-cholinoceptor blocking drugs, the drugs that can dilate bronchial smooth muscle by blocking the M-cholinoceptors, such as ipratropium, anisodamine, etc.
  3.  theophyllines, which reduce cAMP damage mainly by inhibiting phosphodiesterase in order to relieve asthma, such as aminophylline, dyphylline, etc.
  4. drugs inhibiting the release of the active allergy substance such as disodium cromoglycate, etc.
  5. adrenocortical hormones such as beclomethasone (BDP), methylprednisolone, kenacort.
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Structure Chemical Name CAS MF
Zileuton Zileuton 111406-87-2 C11H12N2O2S
Pranlukast Pranlukast 103177-37-3 C27H23N5O4
Tiotropium bromide Tiotropium bromide 136310-93-5 C19H22BrNO4S2
Montelukast sodium Montelukast sodium 151767-02-1 C35H37ClNNaO3S
Seratrodast Seratrodast 112665-43-7 C22H26O4
Suplatast tosilate Suplatast tosilate 94055-76-2 C23H33NO7S2
Roflumilast Roflumilast 162401-32-3 C17H14Cl2F2N2O3
Montelukast Montelukast 158966-92-8 C35H36ClNO3S
Theophylline Theophylline 58-55-9 C7H8N4O2
Albuterol sulfate Albuterol sulfate 51022-70-9 C13H23NO7S
Esculetin Esculetin 305-01-1 C9H6O4
Geraniol Geraniol 106-24-1 C10H18O
MABUTEROL MABUTEROL 56341-08-3 C13H18ClF3N2O
Diprophylline Diprophylline 479-18-5 C10H14N4O4
Repirinast Repirinast 73080-51-0 C20H21NO5
Tralokinumab Tralokinumab 1044515-88-9
Astegolimab Astegolimab 2173054-79-8
(S)-1,2,3,4-tetrahydro-6,7-dihydroxy-1-(3,4,5-trimethoxybenzyl)isoquinolinium chloride (S)-1,2,3,4-tetrahydro-6,7-dihydroxy-1-(3,4,5-trimethoxybenzyl)isoquinolinium chloride 18559-59-6 C19H24ClNO5
Tretoquinol Tretoquinol 30418-38-3 C19H23NO5
guaifylline guaifylline 5634-38-8 C10H14O4.C7H8N4O2
Verlukast Verlukast 120443-16-5 C26H27ClN2O3S2
Valategrast hydrochloride Valategrast hydrochloride 828271-96-1 C30H33Cl4N3O4
MN-221:  KUR-1246 MN-221: KUR-1246 194785-31-4 C24H34N2O9S
Carotegrast methyl Carotegrast methyl 401905-67-7 C28H26Cl2N4O5
Nisbuterol mesylate Nisbuterol mesylate 60734-88-5 C22H27NO6.CH4SO3
4-[1-HYDROXY-2-([1-METHYLETHYL]AMINO)BUTYL]-1,2-BENZENEDIOL METHANESULFONATE 4-[1-HYDROXY-2-([1-METHYLETHYL]AMINO)BUTYL]-1,2-BENZENEDIOL METHANESULFONATE 7279-75-6 C13H21NO3.CH4O3S
Benralizumab Benralizumab 1044511-01-4
Tipelukast Tipelukast 125961-82-2 C29H38O7S
RiMiterol HydrobroMide RiMiterol HydrobroMide 31842-61-2 C12H18BrNO3
7-[3-[[2-(3,5-dihydroxyphenyl)-2-hydroxyethyl]amino]propyl]-3,7-dihydro-1,3-dimethyl-1H-purine-2,6-dione monohydrochloride 7-[3-[[2-(3,5-dihydroxyphenyl)-2-hydroxyethyl]amino]propyl]-3,7-dihydro-1,3-dimethyl-1H-purine-2,6-dione monohydrochloride 13055-82-8 C18H24ClN5O5
Cromitrile Cromitrile 53736-52-0 C20H14N5NaO5
Quazolast Quazolast 86048-40-0 C12H7ClN2O3
Milveterol hydrochloride Milveterol hydrochloride 804518-03-4 C25H30ClN3O4
AMG 853 AMG 853 1169483-24-2 C28H27Cl2FN2O6S
6-(1H-indol-4-yl)-4-(5-((4-isopropylpiperazin-1-yl)methyl)oxazol-2-yl)-1H-indazole 6-(1H-indol-4-yl)-4-(5-((4-isopropylpiperazin-1-yl)methyl)oxazol-2-yl)-1H-indazole 1254036-71-9 C26H28N6O
AZD-7594 AZD-7594 1196509-60-0 C32H32F2N4O6
5H-[1]Benzopyrano[2,3-b]pyridine,5-(1- methyl-4-piperidinylidene)-,(2Z)-2- butenedioate (1:1) 5H-[1]Benzopyrano[2,3-b]pyridine,5-(1- methyl-4-piperidinylidene)-,(2Z)-2- butenedioate (1:1) 39624-65-2 C22H22N2O5
Picumeterol fumarate Picumeterol fumarate 130641-37-1 (C21H29Cl2N3O2)2. C4H4O4
ISOETHARINE HYDROCHLORIDE (250 MG) ISOETHARINE HYDROCHLORIDE (250 MG) 2576-92-3 C13H21NO3.ClH
CLENBUTEROL D9 CLENBUTEROL D9 129138-58-5 C12H9Cl2D9N2O
BAMIFYLLINE BAMIFYLLINE 2016-63-9 C20H27N5O3
2-methylpropyl 4-(6,7-dimethoxyquinazolin-4-yl)piperazine-1-carboxylate hydrochloride 2-methylpropyl 4-(6,7-dimethoxyquinazolin-4-yl)piperazine-1-carboxylate hydrochloride 23256-26-0 C19H27ClN4O4
Sulfonterol hydrochloride Sulfonterol hydrochloride 42461-78-9
TOFIMILAST TOFIMILAST 185954-27-2 C18H21N5S
3-(2-Cyano-2,2-diphenylethyl)-8,8-dimethyl-8-azoniabicyclo[3.2.1]octane bromide 3-(2-Cyano-2,2-diphenylethyl)-8,8-dimethyl-8-azoniabicyclo[3.2.1]octane bromide 850607-58-8 C24H29N2.Br
Oxelumab Oxelumab 1186098-83-8
Ligelizumab Ligelizumab 1322627-61-1
N-[2-hydroxy-5-[1-hydroxy-2-(isopropylamino)ethyl]phenyl]methanesulphonamide monohydrochloride N-[2-hydroxy-5-[1-hydroxy-2-(isopropylamino)ethyl]phenyl]methanesulphonamide monohydrochloride 14816-67-2 C12H21ClN2O4S
AMINOPHYLLINE DIHYDRATE AMINOPHYLLINE DIHYDRATE 5897-66-5 C9H16N6O2
Isamoxole Isamoxole 57067-46-6
Oxarbazole Oxarbazole 35578-20-2 C21H19NO4
Zindotrine Zindotrine 56383-05-2 C11H15N5
5-[(1R)-2-[6-(2,2-difluoro-2-phenyl-ethoxy)hexylamino]-1-hydroxy-ethyl]-8-hydroxy-1H-quinolin-2-one: naphthalene-1,5-disulfonic acid (2:1) 5-[(1R)-2-[6-(2,2-difluoro-2-phenyl-ethoxy)hexylamino]-1-hydroxy-ethyl]-8-hydroxy-1H-quinolin-2-one: naphthalene-1,5-disulfonic acid (2:1) 1044516-17-7 C35H38F2N2O10S2
(R)-BUTAPROST (R)-BUTAPROST 69648-38-0 C24H40O5
1-Acetoxy-2-butyl-4-methoxynaphtalene 1-Acetoxy-2-butyl-4-methoxynaphtalene 99107-52-5 C17H20O3
2-Thiopheneacetic acid, α-hydroxy-α-2-thienyl-, trans-4-[[3-[5-[[[(2R)-2-(1,2-dihydro-8-hydroxy-2-oxo-5-quinolinyl)-2-hydroxyethyl]amino]methyl]-1H-benzotriazol-1-yl]propyl]methylamino]cyclohexyl ester, compd. with 1,2-benzisothiazol-3(2H)-one 1,1-dioxide (1:1) 2-Thiopheneacetic acid, α-hydroxy-α-2-thienyl-, trans-4-[[3-[5-[[[(2R)-2-(1,2-dihydro-8-hydroxy-2-oxo-5-quinolinyl)-2-hydroxyethyl]amino]methyl]-1H-benzotriazol-1-yl]propyl]methylamino]cyclohexyl ester, compd. with 1,2-benzisothiazol-3(2H)-one 1,1-dioxide (1:1) 1648550-37-1 C45H47N7O9S3
Pirolate Pirolate 55149-05-8 C16H15N3O5
WAY-PDA 641 WAY-PDA 641 141184-34-1 C15H20N2O4
ontazolast ontazolast 147432-77-7 C21H25N3O
RS 5186 RS 5186 113817-57-5
Research Grade Lunsekimig Research Grade Lunsekimig 2770858-49-4
5-[4-methoxy-3-[(2S)-norbornan-2-yl]oxy-phenyl]-1,3-diazinan-2-one 5-[4-methoxy-3-[(2S)-norbornan-2-yl]oxy-phenyl]-1,3-diazinan-2-one 135637-46-6 C18H24N2O3
BI 1744 hydrochloride BI 1744 hydrochloride 869477-96-3 C21H27ClN2O5
Batefenterol Succinate Batefenterol Succinate 945905-37-3 C44H48ClN5O11
Ablukast sodium Ablukast sodium 96565-55-8 C28H35NaO8
Itepekimab Itepekimab 2226742-52-3
Verofylline Verofylline 66172-75-6 C12H18N4O2
3,5-bis(acetoxyacetylamino)-4-chlorobenzonitrile 3,5-bis(acetoxyacetylamino)-4-chlorobenzonitrile 123548-56-1 C15H14ClN3O6
4-hydroxy-7-[2-[2-(3-phenethyloxypropylsulfonyl)ethylamino]ethyl]-3H-benzothiazol-2-one hydrochloride 4-hydroxy-7-[2-[2-(3-phenethyloxypropylsulfonyl)ethylamino]ethyl]-3H-benzothiazol-2-one hydrochloride 154189-24-9 C22H29ClN2O5S2
Toreforant Toreforant 952494-46-1 C23H32N6
Pinocembrin Pinocembrin 915133-65-2 C25H30F2N2O4
Tibenelast (sodium) Tibenelast (sodium) 105102-18-9 C13H13NaO4S
THEOPHYLLOL THEOPHYLLOL 8002-89-9 C9H14N4Na2O4
Omalizumab Omalizumab 242138-07-4
AZD-8871 AZD-8871 1435519-06-4 C38H42N6O6S2
Quinterenol sulfate Quinterenol sulfate 13758-23-1 C14H20N2O6S
Pobilukast edamine Pobilukast edamine 137232-03-2 C28H42N2O5S
CINALUKAST CINALUKAST 128312-51-6 C23H28N2O3S
[5-[2-[(tert-butyl)amino]-1-hydroxyethyl]-2-hydroxyphenyl]uronium chloride [5-[2-[(tert-butyl)amino]-1-hydroxyethyl]-2-hydroxyphenyl]uronium chloride 34866-46-1 C13H22ClN3O3
Depemokimab Depemokimab 2243274-14-6
mepolizumab mepolizumab 196078-29-2
Sb-240683 Sb-240683 331243-22-2
umeclidinium umeclidinium 869185-19-3 C29H34NO2+
Nemiralisib succinate Nemiralisib succinate 1364799-98-3 (C26H28N6O)2. C4H6O4
Toreforant tartrate Toreforant tartrate 1203558-77-3 C27H38N6O6
Arofylline Arofylline 136145-07-8 C14H13ClN4O2
1-[(2R)-4-[5-[(4-fluorophenyl)methyl]thiophen-2-yl]but-3-yn-2-yl]-1-hydroxy-urea 1-[(2R)-4-[5-[(4-fluorophenyl)methyl]thiophen-2-yl]but-3-yn-2-yl]-1-hydroxy-urea 154355-76-7 C16H15FN2O2S
PIRIPROST POTASSIUM SALT PIRIPROST POTASSIUM SALT 88851-62-1 C26H34KNO4
reslizumab reslizumab 241473-69-8
Clenpenterol Clenpenterol
Anrukinzumab Anrukinzumab 910649-32-0
etamiphyllin etamiphyllin 314-35-2 C13H21N5O2
etamiphyllin hydrochloride etamiphyllin hydrochloride 17140-68-0 C13H21N5O2.ClH
Tematropium Tematropium 113932-41-5 C20H28NO4.CH3O4S
Benzenemethanol, α-[1-(dimethylamino)ethyl]-, (R*,S*)-(+-)-, compd. with 1,2-benzisothiazol-3(2H)-one 1,1-dioxide (1:1) Benzenemethanol, α-[1-(dimethylamino)ethyl]-, (R*,S*)-(+-)-, compd. with 1,2-benzisothiazol-3(2H)-one 1,1-dioxide (1:1) 75011-63-1 C11H17NO.C7H5NO3S
ablukast ablukast 96566-25-5 C28H34O8
Zinterol hydrochloride Zinterol hydrochloride 38241-28-0 C19H27ClN2O4S
4-(4-Fluorophenyl)-7-[[[5-[(1S)-1-hydroxy-1-(trifluoromethyl)propyl]-1,3,4-oxadiazol-2-yl]amino]methyl]-2H-1-benzopyran-2-one 4-(4-Fluorophenyl)-7-[[[5-[(1S)-1-hydroxy-1-(trifluoromethyl)propyl]-1,3,4-oxadiazol-2-yl]amino]methyl]-2H-1-benzopyran-2-one 910656-27-8 C22H17F4N3O4
Piclamilast Piclamilast 144035-83-6 C18H18Cl2N2O3
Interleukin-12 Interleukin-12 187348-17-0
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