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| | ELASTASE SUBSTRATE IV, COLORIMETRIC Basic information |
| Product Name: | ELASTASE SUBSTRATE IV, COLORIMETRIC | | Synonyms: | SUC-ALA-ALA-PRO-ABU-PNA;SUC-ALA-ALA-PRO-ABU-PNA ; ELASTASE SUBSTRATE IV, COLORIMETRIC;ELASTASE SUBSTRATE IV;ELASTASE SUBSTRATE IV, COLORIMETRIC;Suc-AAP-Abu-pNA;Elastase Colorimetric Substrate IV;SUC-AAP-ABU-PNA;ELASTASE COLORIMETRIC SUBSTRATE IV;Butanamide, N-(3-carboxy-1-oxopropyl)-L-alanyl-L-alanyl-L-prolyl-N-(4-nitrophenyl)-L-2-amino- (9CI) | | CAS: | 108392-27-4 | | MF: | C25H34N6O9 | | MW: | 562.57 | | EINECS: | | | Product Categories: | Pepetides | | Mol File: | Mol File |  |
| | ELASTASE SUBSTRATE IV, COLORIMETRIC Chemical Properties |
| Boiling point | 1014.166±65.00 °C(Press: 760.00 Torr)(predicted) | | density | 1.362±0.06 g/cm3(Temp: 25 °C; Press: 760 Torr)(predicted) | | storage temp. | Store at -20°C | | solubility | ethanol: 1mg/mL
water: soluble | | form | lyophilized solid | | pka | 4.691±0.10(predicted) | | color | white to off-white | | Water Solubility | Water: 1 mg/ml | | Sequence | {Suc}-Ala-Ala-Pro-{Abu}-{pNA} |
| WGK Germany | WGK 1 | | Storage Class | 11 - Combustible Solids |
| | ELASTASE SUBSTRATE IV, COLORIMETRIC Usage And Synthesis |
| Uses | Suc-AAP-Abu-pNA (Colorimetric Elastase Substrate) is a specific substrate for pancreatic elastase (Km = 100 μM; Kcat/Km = 35,300 s-1 M-1 for rat pancreatic elastase; Km = 30 μM; Kcat/Km = 351,000 s-1 M-1 for porcine pancreatic elastase). Suc-AAP-Abu-pNA also promotes OPC migration[1]. | | Biological Activity | Cell permeable: no', 'Primary Target
A specific substrate for pancreatic elastase', 'Product does not compete with ATP.', 'Reversible: no', 'km = 100 μM; kcat/ Km = 35,000 M-1 s-1 for r at pancreatic elastase; Km = 30 μM; kcat/Km = 35,000 M-1 s-1 for porcine | | References | [1] Largman C. Isolation and characterization of rat pancreatic elastase. Biochemistry. 1983 Aug 2;22(16):3763-70. DOI:10.1021/bi00285a008 |
| | ELASTASE SUBSTRATE IV, COLORIMETRIC Preparation Products And Raw materials |
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