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| | tert-butyl hex-5-ynoate Basic information |
| Product Name: | tert-butyl hex-5-ynoate | | Synonyms: | tert-butyl hex-5-ynoate;hex-5-ynoic acid tert-butyl ester;5-Hexynoic acid tert-butyl ester;5-Hexynoic acid, 1,1-dimethylethyl ester;tert-Butyl 5-Hexynoate;Tert-butyl hex-5-ynoate - [B70772];5-hexylyneacidtertbutyl ester | | CAS: | 73448-14-3 | | MF: | C10H16O2 | | MW: | 168.23 | | EINECS: | | | Product Categories: | | | Mol File: | 73448-14-3.mol |  |
| | tert-butyl hex-5-ynoate Chemical Properties |
| Boiling point | 209.7±23.0 °C(Predicted) | | density | 0.929±0.06 g/cm3(Predicted) | | form | Liquid |
| | tert-butyl hex-5-ynoate Usage And Synthesis |
| Uses | tert-Butyl hex-5-ynoate is the linker that can be used for PROTAC synthesis of PROTAC cGAS degrader-1 (HY-172208)[1]. | | References | [1] He P, et al., Discovery of a Novel CRBN-Recruiting cGAS PROTAC Degrader for the Treatment of Ulcerative Colitis. J Med Chem. 2025 Mar 13;68(5):5551-5572. DOI:10.1021/acs.jmedchem.4c02774 |
| | tert-butyl hex-5-ynoate Preparation Products And Raw materials |
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