(R)-(2-CHLORO-3-(TRIFLUOROMETHYL)PHENYL)(1-(5-FLUOROPYRIDIN-2-YL)-4-METHYL-6,7-DIHYDRO-1H-IMIDAZO[4,5-C]PYRIDIN-5(4H)-YL)METHANONE
| 中文名称 | (R)-(2-CHLORO-3-(TRIFLUOROMETHYL)PHENYL)(1-(5-FLUOROPYRIDIN-2-YL)-4-METHYL-6,7-DIHYDRO-1H-IMIDAZO[4,5-C]PYRIDIN-5(4H)-YL)METHANONE |
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| 中文同义词 | 化合物 T27688 |
| 英文名称 | JNJ-54166060 |
| 英文同义词 | (R)-(2-CHLORO-3-(TRIFLUOROMETHYL)PHENYL)(1-(5-FLUOROPYRIDIN-2-YL)-4-METHYL-6,7-DIHYDRO-1H-IMIDAZO[4,5-C]PYRIDIN-5(4H)-YL)METHANONE;JNJ-54166060;Methanone, [2-chloro-3-(trifluoromethyl)phenyl][(4S)-1-(5-fluoro-2-pyridinyl)-1,4,6,7-tetrahydro-4-methyl-5H-imidazo[4,5-c]pyridin-5-yl]-;(S)-JNJ-54166060 |
| CAS号 | 1627900-42-8 |
| 分子式 | C20H15ClF4N4O |
| 分子量 | 438.81 |
| EINECS号 | |
| 相关类别 | |
| Mol文件 | 1627900-42-8.mol |
| 结构式 | ![(R)-(2-CHLORO-3-(TRIFLUOROMETHYL)PHENYL)(1-(5-FLUOROPYRIDIN-2-YL)-4-METHYL-6,7-DIHYDRO-1H-IMIDAZO[4,5-C]PYRIDIN-5(4H)-YL)METHANONE 结构式](CAS/20200611/GIF/1627900-42-8.gif) |
(R)-(2-CHLORO-3-(TRIFLUOROMETHYL)PHENYL)(1-(5-FLUOROPYRIDIN-2-YL)-4-METHYL-6,7-DIHYDRO-1H-IMIDAZO[4,5-C]PYRIDIN-5(4H)-YL)METHANONE 性质
| 沸点 | 586.7±50.0 °C(Predicted) |
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| 密度 | 1.49±0.1 g/cm3(Predicted) |
| 酸度系数(pKa) | 3.72±0.40(Predicted) |
(R)-(2-CHLORO-3-(TRIFLUOROMETHYL)PHENYL)(1-(5-FLUOROPYRIDIN-2-YL)-4-METHYL-6,7-DIHYDRO-1H-IMIDAZO[4,5-C]PYRIDIN-5(4H)-YL)METHANONE 用途与合成方法
(S)-JNJ-54166060 是 JNJ 54166060 的对映异构体。JNJ 54166060 是一种有效的 P2X7 拮抗剂。