ChemicalBook > Product Catalog >Pharmaceutical intermediates >Heterocyclic compound >Thiophene compounds >Diethyl 5-amino-3-methyl-2,4-thiophenedicarboxylate

Diethyl 5-amino-3-methyl-2,4-thiophenedicarboxylate

Diethyl 5-amino-3-methyl-2,4-thiophenedicarboxylate Suppliers list
Company Name: J & K SCIENTIFIC LTD.  
Tel: 18210857532 18210857532
Email: jkinfo@jkchemical.com
Company Name: Meryer (Shanghai) Chemical Technology Co., Ltd.  
Tel: 4006356688 18621169109
Email: market03@meryer.com
Company Name: Alfa Aesar  
Tel: 400-6106006
Email: saleschina@alfa-asia.com
Company Name: TCI (Shanghai) Development Co., Ltd.  
Tel: 021-67121386
Email: Sales-CN@TCIchemicals.com
Company Name: Energy Chemical  
Tel: 400-0056266
Email: sales8178@energy-chemical.com

Diethyl 5-amino-3-methyl-2,4-thiophenedicarboxylate manufacturers

Diethyl 5-amino-3-methyl-2,4-thiophenedicarboxylate Basic information
Product Name:Diethyl 5-amino-3-methyl-2,4-thiophenedicarboxylate
Synonyms:IFLAB-BB F1386-0052;Diethyl 5-amino-3-methyl-2,4-thiophenedicarboxylte;DIETHYL 5-AMINO-3-METHYLTHIOPHENE-2,4-DICARBOXYLATE;DIETHYL 2-AMINO-4-METHYLTHIOPHENE-3,5-DICARBOXYLATE;ART-CHEM-BB B000492;AURORA 879;ASISCHEM S46503;2,4-THIOPHENEDICARBOXYLIC ACID, 5-AMINO-3-METHYL-, DIETHYL ESTER
CAS:4815-30-9
MF:C11H15NO4S
MW:257.31
EINECS:225-388-0
Product Categories:Thiophenes & Benzothiophenes;Thiophenes;Heterocyclic Building Blocks;Building Blocks;Thiophenes & Benzothiophenes;Esters
Mol File:4815-30-9.mol
Diethyl 5-amino-3-methyl-2,4-thiophenedicarboxylate Structure
Diethyl 5-amino-3-methyl-2,4-thiophenedicarboxylate Chemical Properties
Melting point 105-108 °C(lit.)
Boiling point 372.6±37.0 °C(Predicted)
density 1.3137 (rough estimate)
refractive index 1.5500 (estimate)
storage temp. Storage temp. 2-8°C
pka-0.53±0.10(Predicted)
form Crystalline Powder
color Slightly yellow to beige-yellow
CAS DataBase Reference4815-30-9(CAS DataBase Reference)
Safety Information
Hazard Codes Xi
Risk Statements 36/37/38
Safety Statements 26-36-60-37
WGK Germany 3
HazardClass IRRITANT
HS Code 29349990
MSDS Information
ProviderLanguage
SigmaAldrich English
ACROS English
ALFA English
Diethyl 5-amino-3-methyl-2,4-thiophenedicarboxylate Usage And Synthesis
Chemical Propertiesslightly yellow to beige-yellow crystalline powder
UsesDiethyl 5-Amino-3-methylthiophene-2,4-dicarboxylate is used as a reagent in the synthesis of novel pyrazolo-pyrimidinones as dipeptidyl peptidase IV (DPP-IV) inhibitors in diabetes. It is also used in the synthesis of N-phenylthieno[2,3-d]pyrimidin-4-amines which act as inhibitors of fibroblast grow factor receptor 1 and therefore may be further used as anticancer agents.
Diethyl 5-amino-3-methyl-2,4-thiophenedicarboxylate Preparation Products And Raw materials
Raw materialsEthyl 3-oxobutanoate sodium salt-->Ethyl cyanoacetate-->Ethyl acetoacetate
Preparation Products2-Chloromethyl-5-methyl-4-oxo-3,4-dihydro-thieno[2,3-d]pyrimidine-6-carboxylic acid ethyl ester
Tag:Diethyl 5-amino-3-methyl-2,4-thiophenedicarboxylate(4815-30-9) Related Product Information
Diethyl 5-amino-3-methyl-2,4-thiophenedicarboxylate 2,4-Thiophenedicarboxylic acid, 5-[(2-chloroacetyl)amino]-3-methyl-, diethyl ester Diethyl 5-amino-3-(bromomethyl)thiophene-2,4-dicarboxylate Diethyl 5-{[(1,3-benzothiazol-2-ylthio)acetyl]amino}-3-methylthiophene-2,4-dicarboxylate AURORA 1241 AURORA 3822 AURORA 4110 AURORA 1984 AURORA 1228 AURORA 3768 AURORA 1916 AURORA 69 OTAVA-BB BB7014320713 AURORA 8250 AURORA 1286 AURORA 2044 AURORA 3235 AKOS 89944