Catechol O-methyltransferase manufacturers
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| | Catechol O-methyltransferase Basic information |
| Product Name: | Catechol O-methyltransferase | | Synonyms: | S-ADENOSYL-L-METHIONINE:CATECHOL O-METHYLTRANSFERASE;CATHECHOL-O-METHYL TRANSFERASE;EC 2.1.1.6;catechol O-methyltransferase from*porcine liver;Methyltransferase, catechol;CATECHOL-O-METHYL TRANSFERASE, <10 U/ML*;CATECHOL O-METHYLTRANSFERASE FROM &;catechol-o-methyl transferase from hog liver | | CAS: | 9012-25-3 | | MF: | | | MW: | 0 | | EINECS: | 232-727-6 | | Product Categories: | | | Mol File: | Mol File | ![Catechol O-methyltransferase Structure]() |
| | Catechol O-methyltransferase Chemical Properties |
| WGK Germany | 3 | | TSCA | TSCA listed |
| | Catechol O-methyltransferase Usage And Synthesis |
| Uses | Catechol O-methyltransferase, porcine liver (COMT), the magnesium-dependent transfer of methyl groups from S-adenosyl methionine to a hydroxyl group on dopamine, converting it to 3-methoxytyramine. Catechol O-methyltransferase has two forms in tissues, a soluble form (S-COMT) and a membrane-bound form (MB-COMT). Catechol O-methyltransferase is to regulate epinephrine, norepinephrine, and dopamine levels in the brain[1]. | | Definition | Any of a class of enzymesthat catalyze the transfer of a methyl group toan organic molecule. The methyl donor is s-adenosylmethionine, formed from methionine andATP. | | References | [1] Du X, et, al. A catechol-O-methyltransferase that is essential for auditory function in mice and humans. Proc Natl Acad Sci U S A. 2008 Sep 23;105(38):14609-14. DOI:10.1073/pnas.0807219105 |
| | Catechol O-methyltransferase Preparation Products And Raw materials |
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