- CDAP
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- $6.00
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2026-09-02
- CAS:59016-56-7
- Min. Order: 1KG
- Purity: 99%
- CDAP
-
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2026-08-12
- CAS:59016-56-7
- Min. Order: 1KG
- Purity: 98%
- Supply Ability: 1000kgs
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| Product Name: | CDAP | | Synonyms: | 4-(dimethylamino)pyridin-1-ium-1-carbonitrile;N-cyanogen-4-dimethylamino-pyridine tetrafluoroborate;N-CYANO-4-DIMETHYLAMINOPYRIDINIUM TETRA FLUOROBORATE;1-CYANO-4-DIMETHYLAMINO-PYRIDINIUM TETRAFLUOROBORATE;CDAP;CDAP N-Cyano-4-dimethylaminopyridinium tetrafluoroborate;1-Cyano-4-dimethylaminopyridinium tetrafluoroborate,97+%;N-Cyano-4-diMethylaMinopyridiniuM tetrafluoroborat | | CAS: | 59016-56-7 | | MF: | C8H10BF4N3 | | MW: | 234.99 | | EINECS: | | | Product Categories: | proteinmod | | Mol File: | 59016-56-7.mol |  |
| Melting point | 196-200°C | | storage temp. | Inert atmosphere,Store in freezer, under -20°C | | form | Powder | | color | White to yellow | | biological source | synthetic | | Water Solubility | Soluble in water, and acetonitrile. | | λmax | 301nm(CH3CN)(lit.) | | BRN | 5685616 | | InChI | InChI=1S/C8H10N3.BF4/c1-10(2)8-3-5-11(7-9)6-4-8;2-1(3,4)5/h3-6H,1-2H3;/q+1;-1 | | InChIKey | MBLVMDCQDCVKNE-UHFFFAOYSA-N | | SMILES | [B+3]([F-])([F-])([F-])[F-].N(C1=CC=[N+](C#N)C=C1)(C)C |
| Hazard Codes | Xi,Xn | | Risk Statements | 36/37/38-22 | | Safety Statements | 26-36-60-36/37-9 | | RIDADR | 1759 | | WGK Germany | 3 | | F | 3-8-10-21 | | HazardClass | 8 | | PackingGroup | III | | HS Code | 29333990 | | Storage Class | 3 - Flammable liquids | | Hazard Classifications | Acute Tox. 4 Dermal
Acute Tox. 4 Inhalation
Acute Tox. 4 Oral
Eye Irrit. 2
Flam. Liq. 2
Skin Irrit. 2 |
| Chemical Properties | White to yellow powder | | Uses | 1-Cyano-4-(dimethylamino)pyridinium tetrafluoroborate is a cyanylation reagent for protein sulfhydryl groups and used to prepare protein-polysaccharide conjugates. It is employed as an activating agent for polysaccharide resins and conjugation of lipopolysaccharides while retaining endotoxic activity. | | Biological Activity | CDAP is a cyanylation reagent for protein sulfhydryl groups which is used to prepare protein-polysaccharide conjugates. CDAP is also an activating agent for polysaccharide resins and is used for the conjugation of lipopolysaccharides while retaining their endotoxic activity.
CDAP is considered to be a less toxic reagent as compared to cyanogen bromide (CNBr) (a known polysaccharides activator). In addition, CDAP is easier to use as it can be employed at a lower pH and has fewer side reactions. It is known th at CDAP polysaccharide activation efficiency is optimal at pH 9-10. It was also reported th at direct conjugation of protein to CDAP-activated polysaccharides can be performed under mildly alkaline conditions (pH 7-9). It has also been reported th at proteins could also be conjugated to CDAP-activated polysaccharides at pH 5. |
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