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| | Gossypol-acetic acid Basic information |
| Product Name: | Gossypol-acetic acid | | Synonyms: | (±)-Gossypol-acetic aci;acetic acid gossypol 12542-36-8;GOSSYPOLACETATE(GOSSYPOL-ACETICACID);GOSSYPOL ACETATE(RG);Gossypol-acetic acid
1,1',6,6',7,7'-Hexahydroxy-3,3'-dimethyl-5,5'-bis(1-methylethyl)[2,2'-binaphthalene]-8,8'-dicarboxaldehyde-acetic acid;Gossypol-acetic acid, >=98%;Cottonseed extract;Gossypol-acetic acid12542-36-8 | | CAS: | 12542-36-8 | | MF: | C32H34O10 | | MW: | 578.61 | | EINECS: | 623-939-3 | | Product Categories: | chemical reagent;pharmaceutical intermediate;phytochemical;reference standards from Chinese medicinal herbs (TCM).;standardized herbal extract;API;Inhibitors;Aromatic Phenols | | Mol File: | 12542-36-8.mol |  |
| | Gossypol-acetic acid Chemical Properties |
| Melting point | 164-168°C | | storage temp. | −20°C | | solubility | Soluble in acetone or methanol at 5mg/ml | | form | Solid | | color | Yellow to Very Dark Yellow | | Major Application | food and beverages | | InChIKey | NIOHNDKHQHVLKA-UHFFFAOYSA-N | | SMILES | C12C(C(C)C)=C(C(O)=C(C=O)C=1C(O)=C(C1C(C)=CC3C(C(C)C)=C(O)C(O)=C(C=O)C=3C=1O)C(C)=C2)O.C(=O)(O)C | | LogP | 6.157 (est) | | CAS DataBase Reference | 12542-36-8(CAS DataBase Reference) | | EPA Substance Registry System | Gossypol acetic acid (12542-36-8) |
| Hazard Codes | Xn | | Risk Statements | 22-40 | | Safety Statements | 22-36 | | WGK Germany | 3 | | RTECS | MD7360000 | | HS Code | 29153900 | | Storage Class | 11 - Combustible Solids | | Hazard Classifications | Acute Tox. 4 Oral
Carc. 2 |
| | Gossypol-acetic acid Usage And Synthesis |
| Chemical Properties | Derived from the seeds and root bark of Gossypium herbaceum L., a plant of the Malvaceae family | | Uses | Gossypol is a mixture of natural polyphenols isolated from the cotton plant. It causes spermatogenesis arrest in humans and also functions as an anti-malarial agent. Antiinflammatory. Anticancer. | | Biochem/physiol Actions | Reported to inhibit the autolytic conversion of pepsinogen to pepsin. | | IC 50 | Bcl-xL: 0.5-0.6 μM (Ki); Bcl-2: 0.2-0.3 mM (Ki) |
| | Gossypol-acetic acid Preparation Products And Raw materials |
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