Fluo-3FF (potassium salt) manufacturers
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| | Fluo-3FF (potassium salt) Basic information |
| Product Name: | Fluo-3FF (potassium salt) | | Synonyms: | Fluo-3FF (potassium salt);Potassium 2,2'-((2-(2-(6-(bis(carboxylatomethyl)amino)-2,3-difluorophenoxy)ethoxy)-4-(2,7-dichloro-6-oxido-3-oxo-3H-xanthen-9-yl)phenyl)azanediyl)diacetate;N-[2-[2-[2-[bis(carboxymethyl)amino]-5-(2,7-dichloro-6-hydroxy-3-oxo-3H-xanthen-9-yl)phenoxy]ethoxy]-3,4-difluorophenyl]-N-(carboxymethyl)-glycine,pentapotassiumsalt;Pentapotassium, 2-[2-[2-[6-[bis(carboxylatomethyl)amino]-2,3-difluorophenoxy]ethoxy]-N-(carboxylatomethyl)-4-(2,7-dichloro-3-oxido-6 -oxoxanthen-9-yl)anilino]acetate;Fluo-3FF pentapotassium | | CAS: | 348079-14-1 | | MF: | C35H27Cl2F2KN2O13 | | MW: | 831.6 | | EINECS: | | | Product Categories: | | | Mol File: | 348079-14-1.mol |  |
| | Fluo-3FF (potassium salt) Chemical Properties |
| storage temp. | Store at -20°C | | solubility | Water: soluble | | form | A solid |
| | Fluo-3FF (potassium salt) Usage And Synthesis |
| Description | Fluo-3FF is a fluorescent calcium indicator. It is a di-fluorinated analog of Fluo-3 (Item Nos. 20402 | 20403 | 20404) that displays about a 100-fold lower affinity than Fluo-3 for calcium (Kds = 42 and 0.4 μM, respectively). Low affinity calcium indicators are particularly useful for studying compartments with high concentrations of calcium, such as endoplasmic reticulum, where high affinity dyes will be insensitive to luminal fluctuations. Fluo-3FF has excitation/emission maxima of approximately 506 and 526 nm, respectively. | | Uses | Fluo-3FF pentapotassium is a cell-permeable acetoxy-methyl ester of Fluo-3FF, a fluorescent calcium indicator. Fluo-3FF is a di-fluorinated analog of Fluo-3 with a 100-fold lower affinity than Fluo-3 for calcium (Kds=42 and 0.4 M, respectively). For its low affinity, Fluo-3FF is used for studying compartments with high concentrations of calcium, such as endoplasmic reticulum, where high affinity dyes will be insensitive to luminal fluctuations. | | References | [1] GAVRIEL DAVID Ellen F B John N Barrett. Stimulation-induced changes in [ca2+] in lizard motor nerve terminals[J]. Journal of Physiology-London, 2004, 504 1: 83-96. DOI: 10.1111/j.1469-7793.1997.083bf.x |
| | Fluo-3FF (potassium salt) Preparation Products And Raw materials |
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