(αS)-alpha-amino-3-[(4-carboxyphenyl)methyl]-3,4-dihydro-2,4-dioxo-1(2H)-pyrimidinepropanoic acid

Company Name:	3B Pharmachem (Wuhan) International Co.,Ltd.
Tel:	18930552037
Email:	3bsc@sina.com

Company Name:	MedBioPharmaceutical Technology Inc
Tel:	021-69568360 18916172912
Email:	order@med-bio.cn

Company Name:	Beijing Jin Ming Biotechnology Co., Ltd.
Tel:	010-60605840
Email:	psaitong@jm-bio.com

(αS)-alpha-amino-3-[(4-carboxyphenyl)methyl]-3,4-dihydro-2,4-dioxo-1(2H)-pyrimidinepropanoic acid manufacturers

(αS)-alpha-amino-3-[(4-carboxyphenyl)methyl]-3,4-dihydro-2,4-dioxo-1(2H)-pyrimidinepropanoic acid Basic information

Product Name:	(αS)-alpha-amino-3-[(4-carboxyphenyl)methyl]-3,4-dihydro-2,4-dioxo-1(2H)-pyrimidinepropanoic acid
Synonyms:	UBP 282 HCL;(αS)-α-Amino-3-[(4-carboxyphenyl)methyl]-3,4-dihydro-2,4-dioxo-1(2H)-pyrimidinepropanoicacid;UBP 282;(aS)-a-Amino-3-((4-carboxyphenyl)methyl)-3,4-dihydro-2,4-dioxo-1(2H)-pyrimidinepropanoicacid;(alphaS)-alpha-Amino-3-[(4-carboxyphenyl)methyl]-3,4-dihydro-2,4-dioxo-1(2H)-pyrimidinepropanoic acid;1(2H)-Pyrimidinepropanoic acid, α-amino-3-[(4-carboxyphenyl)methyl]-3,4-dihydro-2,4-dioxo-, (αS)-;(αS)-α-Amino-3-[(4-carboxyphenyl)meth yl]-3,4-dihydro-2,4-dioxo-1(2H)-pyrimidinepropanoi c acid;UBP282,UBP 282
CAS:	544697-47-4
MF:	C15H15N3O6
MW:	333.3
EINECS:
Product Categories:	Glutamate receptor
Mol File:	544697-47-4.mol

(αS)-alpha-amino-3-[(4-carboxyphenyl)methyl]-3,4-dihydro-2,4-dioxo-1(2H)-pyrimidinepropanoic acid Chemical Properties

storage temp.	Store at RT
solubility	Soluble to 100 mM in 1eq. NaOH and to 25 mM in 1eq. HCl
form	Powder

Safety Information

MSDS Information

(αS)-alpha-amino-3-[(4-carboxyphenyl)methyl]-3,4-dihydro-2,4-dioxo-1(2H)-pyrimidinepropanoic acid Usage And Synthesis

Uses	UBP 282 is a receptor antagonist that distinguishes between motoneuron and dorsal root kainate receptors.
Biological Activity	AMPA and kainate receptor antagonist. Inhibits AMPA receptor-, but not kainate receptor-mediated currents on spinal neonatal motoneurons yet antagonizes kainate-induced responses on dorsal root C-fibres.
in vivo	On neonatal rat motoneurones UBP-282 (3-CBW) (200 μM) almost completely abolished responses to AMPA while responses to NMDA, kainate and DHPG were 101.6%, 39.4% and 110.5% of control, respectively. UBP-282 can therefore be used to isolate kainate receptor responses from those mediated by AMPA receptors^[1].

(αS)-alpha-amino-3-[(4-carboxyphenyl)methyl]-3,4-dihydro-2,4-dioxo-1(2H)-pyrimidinepropanoic acid Preparation Products And Raw materials

Tag:(αS)-alpha-amino-3-[(4-carboxyphenyl)methyl]-3,4-dihydro-2,4-dioxo-1(2H)-pyrimidinepropanoic acid(544697-47-4) Related Product Information