THP-PEG9-OH manufacturers
- OH-PEG9-THP
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2025-06-07
- CAS:669556-83-6
- Min. Order: 1g
- Purity: >98.00%
- Supply Ability: 1g
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| | THP-PEG9-OH Basic information |
| Product Name: | THP-PEG9-OH | | Synonyms: | THP-PEG9-OH;OH-PEG9-THP;THP-PEG9-OH/3,6,9,12,15,18,21,24-Octaoxahexacosan-1-ol, 26-[(tetrahydro-2H-pyran-2-yl)oxy]-;3,6,9,12,15,18,21,24-Octaoxahexacosan-1-ol, 26-[(tetrahydro-2H-pyran-2-yl)oxy]- | | CAS: | 669556-83-6 | | MF: | C23H46O11 | | MW: | 498.6 | | EINECS: | | | Product Categories: | | | Mol File: | 669556-83-6.mol |  |
| | THP-PEG9-OH Chemical Properties |
| Boiling point | 569.2±50.0 °C(Predicted) | | density | 1.11±0.1 g/cm3(Predicted) | | pka | 14.36±0.10(Predicted) |
| | THP-PEG9-OH Usage And Synthesis |
| Uses | THP-PEG9-OH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. | | Biological Activity | THP-PEG9-OH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. | | IC 50 | PEGs | | References | [1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 |
| | THP-PEG9-OH Preparation Products And Raw materials |
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