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GNMT antibody

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Company Name: Hubei Serenity BioSolutions Co., Ltd.  
Tel: 027-19371278702 18008634902
Email: 19384116026@163.com
GNMT antibody Basic information
Applications Immunogen Background
Product Name:GNMT antibody
Synonyms:GNMT antibody;Rabbit Polyclonal GNMT Antibody
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GNMT antibody Structure
GNMT antibody Chemical Properties
Safety Information
MSDS Information
GNMT antibody Usage And Synthesis
ApplicationsGNMT antibody has been tested by ELISA, Western blot analysis and ICC/IF analysis  to assure specificity and reactivity.
ImmunogenAnti-human GNMT mAb, is derived from hybridization of mouse F0 myeloma cells with spleen cells from BALB/c mice immunized with recombinant human GNMT amino acids 1-295 purified from E. coli.
BackgroundGNMT is an enzyme that catalyzes the conversion of S-adenosyl-L-methionine with glycine to S-adenosyl-L-homocysteine and sarcosine. GNMT is located in the cytoplasm and acts as a homotetramer. Defects in the GNMT gene causes of GNMT deficiency (hypermethioninemia). GNMT affects DNA methylation by regulating the ratio of S-adenosylmethionine to S-adenosylhomocystine and is involved in the detoxification pathway in liver cells. GNMT expression is diminished in human hepatocellular carcinoma (HCC). GNMT catalyzes the methylation of glycine by using s- adenosylmethionine (adomet) to form n-methylglycine (sarcosine) with the concomitant production of s-adenosylhomocysteine (adohcy). GNMT plays an essential role in the regulation of tissue concentration of adomet and of metabolism of methionine.
GNMT antibody Preparation Products And Raw materials
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