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| | 1β-Acetoxypolygodial Basic information |
| Product Name: | 1β-Acetoxypolygodial | | Synonyms: | 1β-Acetoxypolygodial;Acetoxypolygodial;1,2-Naphthalenedicarboxaldehyde, 8-(acetyloxy)-1,4,4a,5,6,7,8,8a-octahydro-5,5,8a-trimethyl-, (1R,4aS,8R,8aS)-;(1R,4aS,8R,8aS)-8-(acetyloxy)-1,4,4a,5,6,7,8,8a-octahydro-5,5,8a-trimethyl-1,2-naphthalenedicarboxaldehyde | | CAS: | 1818425-44-3 | | MF: | C17H24O4 | | MW: | 292.37 | | EINECS: | | | Product Categories: | | | Mol File: | 1818425-44-3.mol |  |
| | 1β-Acetoxypolygodial Chemical Properties |
| Boiling point | 386.6±42.0 °C(Predicted) | | density | 1.10±0.1 g/cm3(Predicted) | | storage temp. | Store at -20°C | | solubility | Soluble in DMSO | | form | A crystalline solid |
| | 1β-Acetoxypolygodial Usage And Synthesis |
| Description | 1β-Acetoxypolygodial is a sesquiterpenoid that has been found in T. lanceolata and has antiprotozoal activity.1,2 It is active against T. cruzi amastigotes and trypomastigotes (GI50s = 57.8 and 72 μM, respectively) but not T. cruzi epimastigotes (GI50 = >100 μM).2 | | References | 1. Deans, R.M., Gardiner, M.G., Horne, J., et al. Isolation and characterization of 1β‐acetoxypolygodial from Tasmannia lanceolata Asian J. Chem. 3(11),1193-1196(2014).
2. Turner, D.N., Just, J., Dasari, R., et al. Activity of natural and synthetic polygodial derivatives against Trypanosoma cruzi amastigotes, trypomastigotes and epimastigotes Nat. Prod. Res. ,(2019). |
| | 1β-Acetoxypolygodial Preparation Products And Raw materials |
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