(24R)-24-Methyl-5α-dammar-25-ene-3β,20-diol

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(24R)-24-Methyl-5α-dammar-25-ene-3β,20-diol Basic information
Product Name:(24R)-24-Methyl-5α-dammar-25-ene-3β,20-diol
Synonyms:(24R)-24-Methyl-5α-dammar-25-ene-3β,20-diol;Caranaubadiol;24β-Methyl-dammar-25-en-3β,20ξ-diol, (Carnanbadiol);Carnaubadiol;Dammar-25-ene-3,20-diol, 24-methyl-, (3β,24R)-
CAS:4547-30-2
MF:C31H54O2
MW:458.76
EINECS:
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Mol File:4547-30-2.mol
(24R)-24-Methyl-5α-dammar-25-ene-3β,20-diol Structure
(24R)-24-Methyl-5α-dammar-25-ene-3β,20-diol Chemical Properties
Melting point 167-168 °C
Boiling point 533.9±33.0 °C(Predicted)
density 0.984±0.06 g/cm3(Predicted)
storage temp. Store at -20°C
solubility Soluble in DMSO
form A solid
pka15.02±0.29(Predicted)
Safety Information
MSDS Information
(24R)-24-Methyl-5α-dammar-25-ene-3β,20-diol Usage And Synthesis
DescriptionCarnaubadiol is a triterpene that has been found in E. corollata and has antiprotozoal activities. It is active against L. infantum promastigotes and amastigotes, as well as T. cruzi trypomastigotes (IC50s = 46.2, 7.8, and 14.9 μM, respectively).
References[1] DAVID M. PIATAK  Kurt A R. Plant investigations IV. Corollatadiol A new triterpene from euphorbia corollata[J]. Tetrahedron Letters, 1972, 13 44: Pages 4525-4528. DOI: 10.1016/s0040-4039(01)94358-8
[2] BUANA C DE ALMEIDA. Antiprotozoal activity of extracts and isolated triterpenoids of “carnauba” (Copernicia prunifera) wax from Brazil.[J]. Pharmaceutical Biology, 2016, 54 12: 3280-3284. DOI: 10.1080/13880209.2016.1224257
(24R)-24-Methyl-5α-dammar-25-ene-3β,20-diol Preparation Products And Raw materials
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