S-(+)-Fluoxetine hydrochloride

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S-(+)-Fluoxetine hydrochloride Basic information
Product Name:S-(+)-Fluoxetine hydrochloride
Synonyms:(S)-N-Methyl-3-(4-trifluoroMethylphenoxy)-3-phenylpropylaMine Hydrochloride;(γS)-N-Methyl-γ-[4-(trifluoroMethyl)phenoxy]benzenepropanaMine Hydrochloride;Fluoxetine S-IsoMer;(S)-(+)-N-Methyl-3-(4-trifluoromethylphenoxy)-3-phenylpropylamine HCl;(S)-3[4(TRIFLUOROMETHYL)PHENOXY]-N-METHYL-3-PHENYLPROPAN-1-AMINE HYDROCHLORIDE;N-methyl-2-phenyl-5-thiazolamine hydrochloride;(S)-Fluoxetine HCl;Fluoxetine HCl S-Isomer
CAS:114247-06-2
MF:C17H19ClF3NO
MW:345.79
EINECS:
Product Categories:Biogenic Amine Transport Inhibitors;Biogenic Amine Transport InhibitorsObesity Research;Neurotransmission;Neurotransmission (Obesity);Neurotransmitters;Amines;Aromatics;Chiral Reagents;Intermediates & Fine Chemicals;Pharmaceuticals
Mol File:114247-06-2.mol
S-(+)-Fluoxetine hydrochloride Structure
S-(+)-Fluoxetine hydrochloride Chemical Properties
Melting point 140-142°C
storage temp. room temp
solubility H2O: 18 mg/mL, soluble
form solid
color white
Optical Rotation[α]/D +14 to +19°, c =1 in chloroform-d
Water Solubility H2O: soluble ≥20mg/mL
Stability:Hygroscopic
InChI1S/C17H18F3NO.ClH/c1-21-12-11-16(13-5-3-2-4-6-13)22-15-9-7-14(8-10-15)17(18,19)20;/h2-10,16,21H,11-12H2,1H3;1H/t16-;/m0./s1
InChIKeyGIYXAJPCNFJEHY-NTISSMGPSA-N
SMILESCl.CNCC[C@H](Oc1ccc(cc1)C(F)(F)F)c2ccccc2
Safety Information
Hazard Codes Xn,N
Risk Statements 22-50/53
Safety Statements 36/37-60-61
RIDADR UN 3077 9/PG 3
WGK Germany 3
Storage Class11 - Combustible Solids
Hazard ClassificationsAcute Tox. 4 Oral
Aquatic Acute 1
Aquatic Chronic 1
MSDS Information
ProviderLanguage
SigmaAldrich English
S-(+)-Fluoxetine hydrochloride Usage And Synthesis
Chemical PropertiesWhite Solid
UsesA selective serotonin reuptake inhibitor (SSRI).S-(+)-Fluoxetine hydrochloride is used as an antidepressant.
DefinitionChEBI: A hydrochloride obtained by reaction of (S)-fluoxetine with one equivalent of hydrochloric acid.
General DescriptionFluoxetine hydrochloride or fluoxetine hcl is a psychotropic agent and one of the initial members of the anti-depressant class of drugs known as selective serotonin-reuptake inhibitors (SSRIs). It is the active ingredient of Prozac.
Biochem/physiol ActionsFluoxetine hcl (hydrochloride) is a selective serotonin reuptake inhibitor and functions as an antidepressant. This drug works at presynaptic terminals where it prevents the reuptake of serotonin, resulting in the accumulation of serotonin in extracellular fluid at synapses.
S-(+)-Fluoxetine hydrochloride Preparation Products And Raw materials
Tag:S-(+)-Fluoxetine hydrochloride(114247-06-2) Related Product Information
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