- 2014 hot sale! 4-Bro
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- $20.10
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2021-11-15
- CAS:2362-12-1
- Min. Order: 1KG
- Purity: 99%
- Supply Ability: 500ton/Month
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| | 4-Bromo-2-methylphenol Basic information |
| | 4-Bromo-2-methylphenol Chemical Properties |
| Melting point | 63-67 °C | | Boiling point | 63-67°C | | density | 1.3839 (rough estimate) | | refractive index | 1.5772 (estimate) | | storage temp. | Keep in dark place,Sealed in dry,Room Temperature | | pka | 9.74±0.18(Predicted) | | form | powder to lump | | color | White to Light yellow to Light orange | | Water Solubility | Slightly soluble in water. | | InChI | InChI=1S/C7H7BrO/c1-5-4-6(8)2-3-7(5)9/h2-4,9H,1H3 | | InChIKey | IWJGMJHAIUBWKT-UHFFFAOYSA-N | | SMILES | C1(O)=CC=C(Br)C=C1C | | CAS DataBase Reference | 2362-12-1(CAS DataBase Reference) | | NIST Chemistry Reference | 4-Bromo-2-methylphenol(2362-12-1) |
| Hazard Codes | Xi,Xn | | Risk Statements | 36/37/38-22 | | Safety Statements | 26-36/37/39-24/25 | | WGK Germany | WGK 3 | | RTECS | GO6868000 | | Hazard Note | Irritant | | HazardClass | IRRITANT, IRRITANT-HARMFUL | | HS Code | 29089990 | | Storage Class | 13 - Non Combustible Solids | | Hazard Classifications | Acute Tox. 4 Oral |
| | 4-Bromo-2-methylphenol Usage And Synthesis |
| Chemical Properties | White solid | | Uses | 4-Bromo-2-methylphenol, is used as a pharmaceutical intermediate. | | Synthesis | o-Toluene ( 1 mmol) was dissolved in 3 mL of ethanol and 1.02 was added to the resulting mixture.
mmol of N-bromosuccinimide purified by recrystallization. The resulting mixture was stirred at room temperature for 1
The progress of the reaction was monitored by passing a TLC spot plate to ensure that all the ingredients were fully reacted, and then the solvent ethanol was removed under reduced pressure. Then 10 mL of ethyl acetate and 10 m were added to the reaction system.
L distilled water, the mixture was transferred to a partition funnel to separate the organic ( ethyl acetate ) fraction, and then ethyl acetate ( 2 7 m ) was used to extract the water.
L) to extract the aqueous layer. All the ethyl acetate extracts were combined and dried over anhydrous Mg SO4, the organic solvent was spun dry, and the crude product was purified by column chromatographic separation to give the target product molecule 4-bromo-2-methylphenol. |
| | 4-Bromo-2-methylphenol Preparation Products And Raw materials |
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