L-Alanine, N-[[P(S),2'R]-2-amino-2'-deoxy-2'-fluoro-N,2'-dimethyl-P-phenyl-5'-adenylyl]-, 1-methylethyl ester
概述 用途与合成方法 MSDS L-Alanine, N-[[P(S),2'R]-2-amino-2'-deoxy-2'-fluoro-N,2'-dimethyl-P-phenyl-5'-adenylyl]-, 1-methylethyl ester价格(试剂级) 上下游产品信息
| 中文名称 | L-Alanine, N-[[P(S),2'R]-2-amino-2'-deoxy-2'-fluoro-N,2'-dimethyl-P-phenyl-5'-adenylyl]-, 1-methylethyl ester |
|---|---|
| 中文同义词 | AT-527 游离碱;AT-527 碱式;化合物BEMNIFOSBUVIR;((((2R,3R,4R,5R)-5-(2-氨基-6-(甲基氨基)-9H-嘌呤-9-基)-4-氟-3-羟基-4-甲基四氢呋喃-2-基)甲氧基)(苯氧基)磷酰基)-L-丙氨酸异丙基酯;化合物BEMNIFOSBUVIR,10 MM DMSO 溶液 |
| 英文名称 | L-Alanine, N-[[P(S),2'R]-2-amino-2'-deoxy-2'-fluoro-N,2'-dimethyl-P-phenyl-5'-adenylyl]-, 1-methylethyl ester |
| 英文同义词 | L-Alanine, N-[[P(S),2'R]-2-amino-2'-deoxy-2'-fluoro-N,2'-dimethyl-P-phenyl-5'-adenylyl]-, 1-methylethyl ester;AT-511;guanosine,pangenotypic,Hepatitis C virus,SARS coronavirus,inhibit,HCV,Bemnifosbuvir,Inhibitor,antiviral,AT 511,SARS-CoV,nucleotide,phosphoramidate,AT511;Isopropyl ((((2R,3R,4R,5R)-5-(2-amino-6-(methylamino)-9H-purin-9-yl)-4-fluoro-3-hydroxy-4-methyltetrahydrofuran-2-yl)methoxy)(phenoxy)phosphoryl)-L-alaninate;propan-2-yl (2S)-2-{[(S)-{[(2R,3R,4R,5R)-5-[2-amino-6-(methylamino)-9H-purin-9-yl]-4-fluoro-3-hydroxy-4-methyloxolan-2-yl]methoxy}(phenoxy)phosphoryl]amino}propanoate;Bemnifosbuvir(AT-511);AT-511(Bemnifosbuvir free base);Bemnifosbuvir, 10 mM in DMSO |
| CAS号 | 1998705-64-8 |
| 分子式 | C24H33FN7O7P |
| 分子量 | 581.53 |
| EINECS号 | |
| 相关类别 | |
| Mol文件 | 1998705-64-8.mol |
| 结构式 | ![L-Alanine, N-[[P(S),2'R]-2-amino-2'-deoxy-2'-fluoro-N,2'-dimethyl-P-phenyl-5'-adenylyl]-, 1-methylethyl ester 结构式](CAS/20211123/GIF/1998705-64-8.gif) |
L-Alanine, N-[[P(S),2'R]-2-amino-2'-deoxy-2'-fluoro-N,2'-dimethyl-P-phenyl-5'-adenylyl]-, 1-methylethyl ester 性质
| 沸点 | 781.9±70.0 °C(Predicted) |
|---|---|
| 密度 | 1.54±0.1 g/cm3(Predicted) |
| 储存条件 | 4°C, protect from light |
| 溶解度 | DMSO：100 mg/mL（171.96 mM；需要超声波） |
| 形态 | 固体 |
| 酸度系数(pKa) | 12.43±0.70(Predicted) |
| 颜色 | 米白色至浅黄色 |
| InChIKey | OISLSHLAXHALQZ-NPGFSVGSNA-N |
| SMILES | C[C@]1([C@@H]([C@@H](COP(=O)(N[C@@H](C)C(=O)OC(C)C)OC2C=CC=CC=2)O[C@H]1N1C=NC2=C(N=C(N)N=C12)NC)O)F |&1:1,2,3,9,25,r| |
L-Alanine, N-[[P(S),2'R]-2-amino-2'-deoxy-2'-fluoro-N,2'-dimethyl-P-phenyl-5'-adenylyl]-, 1-methylethyl ester 用途与合成方法
Bemnifosbuvir 是一种有效的具有口服活性的 HCV 病毒复制抑制剂。Bemnifosbuvir 有效抑制 SARS-CoV-2 (COVID-19) 感染 (EC90=0.47 μM)。Bemnifosbuvir 具有全基因型抗病毒活性。
安全信息
| 更新日期 | 产品编号 | 产品名称 | CAS号 | 包装 | 价格 |
|---|---|---|---|---|---|
| 2026/09/15 | HY-137958A | Bemnifosbuvir | 1998705-64-8 | 1 mg | 669元 |
| 2026/09/15 | HY-137958A | L-Alanine, N-[[P(S),2'R]-2-amino-2'-deoxy-2'-fluoro-N,2'-dimethyl-P-phenyl-5'-adenylyl]-, 1-methylethyl ester Bemnifosbuvir | 1998705-64-8 | 5 mg | 1488元 |