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4-Hydroxy-2-methyl-2H-1,2-benzothiazine-3-carboxylic acid isopropyl ester 1,1-dioxide

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4-Hydroxy-2-methyl-2H-1,2-benzothiazine-3-carboxylic acid isopropyl ester 1,1-dioxide Basic information
Product Name:4-Hydroxy-2-methyl-2H-1,2-benzothiazine-3-carboxylic acid isopropyl ester 1,1-dioxide
Synonyms:Isopropyl-4-hydroxy-2-methyl-2H-1,2-benzothiazine-3-carboxylate-1,1-dioxide;4-HYDROXY-2-METHYL-1H-1,2-BENZOTHIAZINE-3-CARBOXYLICACIDISOPROPYLESTER-1,1-DIOXIDE;4-hydroxy-2-methyl-2H-1,2-benzothiazine-3-carboxylic acid isopropylester-1,1-dioxide (intermediate of piroxicam);Isopropyl 2-methyl-4-hydroxy-2H-1,2-benzothiazine-3-carboxylater 1,1-dioxide;Isopropyl 4-Hydroxy-2-methyl-2H-1,2-benzothiazine-3-carboxylate 1,1-Dioxide (Piroxicam Impurity L);Isopropyl 4-Hydroxy-2-methyl-;Meloxicam Related Compound C (30 mg) (Isopropyl 4-hydroxy-2-methyl-2H-1,2-benzothiazine-3-carboxylate-1,1-dioxide);MeloxicaM IMpurity F
CAS:118854-48-1
MF:C13H15NO5S
MW:297.33
EINECS:
Product Categories:Aromatics;Impurities;Intermediates & Fine Chemicals;Pharmaceuticals;Sulfur & Selenium Compounds;Organic acids;(intermediate of piroxicam)
Mol File:118854-48-1.mol
4-Hydroxy-2-methyl-2H-1,2-benzothiazine-3-carboxylic acid isopropyl ester 1,1-dioxide Structure
4-Hydroxy-2-methyl-2H-1,2-benzothiazine-3-carboxylic acid isopropyl ester 1,1-dioxide Chemical Properties
Melting point 200 °C
Boiling point 450.5±55.0 °C(Predicted)
density 1.408
storage temp. -20°C Freezer, Under inert atmosphere
solubility Chloroform (Slightly), Methanol (Slightly)
pka4.50±1.00(Predicted)
color White to Off-White
Major Applicationpharmaceutical
InChI1S/C13H15NO5S/c1-8(2)19-13(16)11-12(15)9-6-4-5-7-10(9)20(17,18)14(11)3/h4-8,15H,1-3H3
InChIKeyZHWSBDIYCSOTBY-UHFFFAOYSA-N
Safety Information
Hazard Codes Xi
Risk Statements 36/37/38
Safety Statements 26
WGK Germany WGK 3
HS Code 2934990002
Storage Class6.1D - Non-combustible acute toxic Cat.3
toxic hazardous materials or hazardous materials causing chronic effects
Hazard ClassificationsAcute Tox. 3 Oral
MSDS Information
4-Hydroxy-2-methyl-2H-1,2-benzothiazine-3-carboxylic acid isopropyl ester 1,1-dioxide Usage And Synthesis
UsesPiroxicam Impurity L. Also an impurity found in meloxicam (M216100). Meloxicam USP Related Compound C.
4-Hydroxy-2-methyl-2H-1,2-benzothiazine-3-carboxylic acid isopropyl ester 1,1-dioxide Preparation Products And Raw materials
Preparation ProductsN-Methylsaccharin
Tag:4-Hydroxy-2-methyl-2H-1,2-benzothiazine-3-carboxylic acid isopropyl ester 1,1-dioxide(118854-48-1) Related Product Information
2-Methyl-4-hydroxy-2H-1,2-benzisothiazine-3-carboxylic acid ethyl ester-1,1-diox 2-[(5-Methyl-2-thiazolyl)amino]-2-oxoacetic Acid 5Carboxy Meloxicam Meloxicam EP Impurity D 2H-1,2-Benzothiazine-3-carboxaMide, 4-Methoxy-2-Methyl-N-(5-Methyl-2-thiazolyl)-, 1,1-dioxide Benzoic acid, 2-[(methylamino)sulfonyl]- Meloxicam Impurity 1 HCl 5Hydroxy Meloxicam 5-(2-Aminopropyl)-1-[3-(benzoyloxy)propyl]-2,3-dihydro-1H-indole-7-carbonitrile Piroxicam Formic acid isopropyl ester 4-Hydroxy-2-methyl-2H-1,2-benzothiazine-3-carboxylic acid isopropyl ester 1,1-dioxide 2-Methyl-4-hydroxy-2H-1,2-benzothiazine-3-carboxylic acid ethyl ester 1,1-dioxide Methyl 4-hydroxy-2H-1,2-benzothiazine-3-carboxylate 1,1-dioxide