| Company Name: |
Artis Biotech Co. Ltd.
|
| Tel: |
19138486554; 18108108965 |
| Email: |
sales@artisbio.com |
| Products Intro: |
Product Name:Tauroursodeoxycholic Acid-[d4] Sodium Salt/Tauroursodeoxycholic acid-[d4] sodium
CAS:2410279-95-5
Purity:98%HPLC Package:1mg;5mg;10mg
|
| Company Name: |
ChemeGen
|
| Tel: |
18818260767 |
| Email: |
2625930290@qq.com |
| Products Intro: |
Product Name:Tauroursodeoxycholic Acid-d4 sodium salt
CAS:2410279-95-5
Purity:98% Package:10 mg;50 mg;100 mg;500 mg;1 g;5 g;10 g
|
| Company Name: |
Reer Technology (Shanghai) Co., LTD
|
| Tel: |
021-64400900 15800436310 |
| Email: |
bessey@reertech.com |
| Products Intro: |
Product Name:TAUROURSODEOXYCHOLIC ACID, SODIUM SALT(2,2,4,4-D4, 98%) 100 UG/ML IN METHANOL
CAS:2410279-95-5
Purity:98% Package:1 ML Remarks:DLM-9882-C
|
| Company Name: |
CHINA ISOTOPE CO., LIMITED
|
| Tel: |
02151600108 13062666369 |
| Email: |
info@isotopechem.com |
| Products Intro: |
Product Name:Tauroursodeoxycholic Acid-d4 (sodium salt)
CAS:2410279-95-5
Purity:Purity: >=98% Package:500ug Remarks:CA32985
|
| Company Name: |
Shanghai Yifei Biotechnology Co. , Ltd.
|
| Tel: |
021-65675885 18964387627 |
| Email: |
customer_service@efebio.com |
| Products Intro: |
Product Name:Tauroursodeoxycholic Acid-d4 (sodium salt)
CAS:2410279-95-5
Purity:95% Package:500μg
|
|
| | Tauroursodeoxycholic Acid-d4 (sodium salt) Basic information |
| Product Name: | Tauroursodeoxycholic Acid-d4 (sodium salt) | | Synonyms: | Taurine ursodeoxycholic acid-d4 sodium salt;Tauroursodeoxycholic Acid-[d4] Sodium Salt/Tauroursodeoxycholic acid-[d4] sodium;TAUROURSODEOXYCHOLICACID,SODIUMSALT(2,2,4,4-D4) IN METHANOL;Tauroursodeoxycholic Acid-[d4] Sodium Salt in Methanol;D4-Tauroursodeoxycholic Acid Sodium Salt;Tauroursodeoxycholic acid, sodium salt (2,2,4,4-D?, 98%);Tauroursodeoxycholic acid, sodium salt (2,2,4,4-D?, 98%) 100 μg/mL in methanol;Tauroursodeoxycholate-D4 Sodium (Standard) | | CAS: | 2410279-95-5 | | MF: | C26H46NNaO6S | | MW: | 523.7 | | EINECS: | | | Product Categories: | | | Mol File: | 2410279-95-5.mol |  |
| | Tauroursodeoxycholic Acid-d4 (sodium salt) Chemical Properties |
| storage temp. | -20°C | | solubility | DMF: 25 mg/ml; DMSO: 20 mg/ml; Ethanol: 1 mg/ml; PBS (pH 7.2): 1 mg/ml | | form | A crystalline solid | | color | White to off-white | | CAS Number Unlabeled | 35807-85-3 |
| WGK Germany | WGK 2 | | Storage Class | 3 - Flammable liquids | | Hazard Classifications | Acute Tox. 3 Dermal
Acute Tox. 3 Inhalation
Acute Tox. 3 Oral
Flam. Liq. 2
STOT SE 1 |
| | Tauroursodeoxycholic Acid-d4 (sodium salt) Usage And Synthesis |
| Description | Tauroursodeoxycholic acid-d4 (TUDCA-d4) is intended for use as an internal standard for the quantification of tauroursodeoxycholic acid by GC- or LC-MS. TUDCA is a taurine-conjugated form of the secondary bile acid ursodeoxycholic acid .1,2 TUDCA is found in small quantities in human bile but at a higher concentration in the bile of black bears.2 It demonstrates anti-apoptotic activity in rodent models of tauopathy, Huntington's disease, ischemic brain injury, and retinal disorders.3,2 | | Uses | Tauroursodeoxycholate-d4 (sodium) is the deuterium labeled Tauroursodeoxycholate sodium. Tauroursodeoxycholate (Tauroursodeoxycholic acid; TUDCA) sodium is an endoplasmic reticulum (ER) stress inhibitor. Tauroursodeoxycholate significantly reduces expression of apoptosis molecules, such as caspase-3 and caspase-12. Tauroursodeoxycholate also inhibits ERK. | | References | 1. Beuers, U. Effects of bile acids on hepatocellular signaling and secretion Yale J. Biol. Med. 70(4),341-346(1997).
2. Boatright, J.H., Nickerson, J.M., Moring, A.G., et al. Bile acids in treatment of ocular disease J. Ocul. Biol. Dis. Infor. 2(3),149-159(2009).
3. Vang, S., Longley, K., Steer, C.J., et al. The unexpected uses of urso- and tauroursodeoxycholic acid in the treatment of non-liver diseases Glob. Adv. Health Med. 3(3),58-69(2014). |
| | Tauroursodeoxycholic Acid-d4 (sodium salt) Preparation Products And Raw materials |
|