Azido-PEG3-chloroacetamide

Azido-PEG3-chloroacetamide Suppliers list
Company Name: Xi'an Confluore Biological Technology Co., Ltd.  
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Company Name: Jilin Chinese Academy of Sciences - Yanshen Technology Co., Ltd  
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Company Name: Jilin Chinese Academy of Sciences-yanshen Technology  
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Company Name: Shanghai Yanfen Biochemical Technology Co.,LTD  
Tel: 13611955358 15002190549
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Azido-PEG3-chloroacetamide Basic information
Product Name:Azido-PEG3-chloroacetamide
Synonyms:Azido-PEG3-chloroacetamide;N-(2-{2-[2-(2-azidoethoxy)ethoxy]ethoxy}ethyl)-2-chloroacetamide
CAS:604766-23-6
MF:C10H19ClN4O4
MW:294.74
EINECS:
Product Categories:
Mol File:604766-23-6.mol
Azido-PEG3-chloroacetamide Structure
Azido-PEG3-chloroacetamide Chemical Properties
Safety Information
MSDS Information
Azido-PEG3-chloroacetamide Usage And Synthesis
UsesAzido-PEG3-chloroacetamide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Azido-PEG3-chloroacetamide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
IC 50PEGs
References[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005
Azido-PEG3-chloroacetamide Preparation Products And Raw materials
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