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| | DAPHNIN Basic information |
| Product Name: | DAPHNIN | | Synonyms: | Daphin;7-β-D-Glucopyranosyloxy-8-hydroxy-2H-1-benzopyran-2-one;8-Hydroxy-2-oxo-2H-1-benzopyran-7-yl β-D-glucopyranoside;8-Hydroxy-7-(β-D-glucopyranosyloxy)-2H-1-benzopyran-2-one;8-Hydrroxycoumarin-7-O-glucoside;8-hydroxy-7-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-chromen-2-one;8-hydroxy-7-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxychromen-2-one;8-hydroxy-7-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-methylol-tetrahydropyran-2-yl]oxy-coumarin | | CAS: | 486-55-5 | | MF: | C15H16O9 | | MW: | 340.28 | | EINECS: | | | Product Categories: | | | Mol File: | 486-55-5.mol |  |
| | DAPHNIN Chemical Properties |
| Melting point | 216-217 °C | | alpha | D22 -124° (15 mg in 4 ml MeOH); D22 -115° (abs MeOH) (Wessely, Sturm); D15 -84.2° (MeOH) (Hattori) | | Boiling point | 670.0±55.0 °C(Predicted) | | density | 1.679±0.06 g/cm3(Predicted) | | storage temp. | -20°C, protect from light | | pka | 6.87±0.20(Predicted) | | form | Solid | | color | Light brown to khaki | | InChI | 1S/C15H16O9/c16-5-8-10(18)12(20)13(21)15(23-8)22-7-3-1-6-2-4-9(17)24-14(6)11(7)19/h1-4,8,10,12-13,15-16,18-21H,5H2/t8-,10-,12+,13-,15-/m1/s1 | | InChIKey | HOIXTKAYCMNVMY-PVOAASPHSA-N | | SMILES | O1[C@H]([C@@H]([C@H]([C@@H]([C@H]1CO)O)O)O)Oc2c(c3[o][c](ccc3cc2)=O)O |
| WGK Germany | WGK 3 | | Storage Class | 11 - Combustible Solids |
| | DAPHNIN Usage And Synthesis |
| Uses | Daphnin is one of the major coumarin bioactive components with antibacterial activity. Daphnin is isolated from the whole herb of Daphne odora (Thunb.), which is a folk medicine in China for the relief of fever[1][2]. | | Definition | ChEBI: Daphnin is a beta-D-glucoside. It is functionally related to a 7,8-dihydroxycoumarin. | | References | [1] Zhu J, et al. Investigation the interaction of Daphnin with human serum albumin using optical spectroscopy and molecular modeling methods. Spectrochim Acta A Mol Biomol Spectrosc. 2012 Sep;95:252-7. DOI:10.1016/j.saa.2012.04.099
[2] Shakeel-U-Rehman, et al. Isolation, characterisation and antibacterial activity studies of coumarins from Rhododendron lepidotum Wall. ex G. Don, Ericaceae. Rev. bras. farmacogn. vol.20 no.6 Curitiba Dec. 2010 Epub Nov 12, 2010. |
| | DAPHNIN Preparation Products And Raw materials |
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