- Erythrodiol
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- $35.00
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2026-07-27
- CAS:545-48-2
- Purity: 99.94%
- Supply Ability: 10g
- Erythrodiol
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- $45.00
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2025-05-23
- CAS:545-48-2
- Min. Order: 1kg
- Purity: 99%
- Supply Ability: 20 tons
- Erythrodiol
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- $3.00
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2020-01-19
- CAS:545-48-2
- Min. Order: 1KG
- Purity: 98%
- Supply Ability: 1kg,5kg,50kg
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| | Erythrodiol Basic information |
| | Erythrodiol Chemical Properties |
| Melting point | 230-231 °C(lit.) | | Boiling point | 520.5±50.0 °C(Predicted) | | density | 1.05±0.1 g/cm3(Predicted) | | storage temp. | -20°C Freezer, Under inert atmosphere | | solubility | Chloroform (Slightly, Sonicated), Methanol (Slightly) | | pka | 15.09±0.10(Predicted) | | form | Solid | | color | White to Off-White | | Water Solubility | insoluble in water | | BRN | 2340203 | | Major Application | food and beverages | | Cosmetics Ingredients Functions | ANTIOXIDANT
SKIN CONDITIONING | | InChIKey | PSZDOEIIIJFCFE-MMIPUHLFNA-N | | SMILES | [C@@]12(C)CC[C@@]3(CO)CCC(C)(C)C[C@@]3([H])C1=CC[C@]1([H])[C@@]3(C)CC[C@H](O)C(C)(C)[C@]3([H])CC[C@@]21C |&1:0,4,13,18,20,24,29,33,r| | | LogP | 9.180 (est) | | CAS DataBase Reference | 545-48-2(CAS DataBase Reference) |
| Risk Statements | 22 | | Safety Statements | 2-45 | | WGK Germany | 3 | | F | 10-23 | | Storage Class | 11 - Combustible Solids |
| | Erythrodiol Usage And Synthesis |
| Description | Erythrodiol is a triterpene that has been found in olive oil and has diverse biological activities. It induces relaxation of isolated rat aortic rings precontracted with phenylephrine (EC50 = 3.38 μM). Erythrodiol inhibits the growth of HT-29 adenocarcinoma cells (EC50 = 48.8 μM). It induces production of reactive oxygen species (ROS) and apoptosis in MCF-7 cells when used at a concentration of 100 μM. Topical administration of erythrodiol (0.5 mg/ear) reduces ear edema and myeloperoxidase (MPO) activity induced by phorbol 12-myristate 13-acetate (TPA; ) in mice. | | Uses | It is an essential reagent in the synthesis of aminopropoxytriterpenoids that have anticancer activity. 3β-Erythrodiol has pharmacological property as a vasodilatory agent. It may have interesting therapeutic potential as a new vasodilator drug, for protecting the cardiovascular system. | | Definition | ChEBI: Erythrodiol is a pentacyclic triterpenoid that is beta-amyrin in which one of the hydrogens of the methyl group at position 28 has been replaced by a hydroxy group. It is a plant metabolite found in olive oil as well as in Rhododendron ferrugineum and other Rhododendron species. It has a role as a plant metabolite. It is a pentacyclic triterpenoid, a primary alcohol, a secondary alcohol and a diol. It is functionally related to a beta-amyrin. | | References | [1] ROSALíA RODRíGUEZ-RODRíGUEZ. Potential vasorelaxant effects of oleanolic acid and erythrodiol, two triterpenoids contained in “orujo” olive oil, on rat aorta.[J]. British Journal of Nutrition, 2004, 92 4: 635-642. DOI: 10.1079/bjn20041231
[2] M. EMíLIA JUAN. Erythrodiol, a natural triterpenoid from olives, has antiproliferative and apoptotic activity in HT-29 human adenocarcinoma cells[J]. Molecular Nutrition & Food Research, 2008, 52 5: 595-599. DOI: 10.1002/mnfr.200700300
[3] YOSRA ALLOUCHE. Antioxidant, Antiproliferative, and Pro-apoptotic Capacities of Pentacyclic Triterpenes Found in the Skin of Olives on MCF-7 Human Breast Cancer Cells and Their Effects on DNA Damage[J]. Journal of Agricultural and Food Chemistry, 2010, 59 1: 121-130. DOI: 10.1021/jf102319y
[4] SALVADOR MáEZ. Effect of selected triterpenoids on chronic dermal inflammation[J]. European journal of pharmacology, 1997, 334 1: Pages 103-105. DOI: 10.1016/s0014-2999(97)01187-4 |
| | Erythrodiol Preparation Products And Raw materials |
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