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Atolide

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Atolide Suppliers list
Company Name: SynAsst Chemical.  
Tel: 021-60343070
Email:
Company Name: TargetMol Chemicals Inc.  
Tel: 15002134094
Email: marketing@targetmol.cn
Company Name: Alchem Pharmtech,Inc.  
Tel: 8485655694
Email: sales@alchempharmtech.com
Company Name: TargetMol Chemicals Inc.  
Tel: +1-781-999-5354;
Email: support@targetmol.com
Atolide Basic information
Product Name:Atolide
Synonyms:2-Amino-N-(4-diethylamino-2-methylphenyl)benzamide;Go 1213;W 5733;Atolide;Benzamide, 2-amino-N-[4-(diethylamino)-2-methylphenyl]-
CAS:16231-75-7
MF:C18H23N3O
MW:297.39
EINECS:
Product Categories:
Mol File:16231-75-7.mol
Atolide Structure
Atolide Chemical Properties
Melting point 153-154 °C
Boiling point 415.7±45.0 °C(Predicted)
density 1.153±0.06 g/cm3(Predicted)
pka12.87±0.70(Predicted)
Safety Information
MSDS Information
Atolide Usage And Synthesis
OriginatorAtolide,ZYF Pharm Chemical
UsesAnticonvulsant.
Manufacturing Process0.8 kg (4.5 moles) of freshly distilled 2-amino-5-diethylaminotoluene is mixed thoroughly with 0.75 kg (4.5 moles) of isatoic acid anhydride and the mixture heated to 100°C with stirring for three hours. The product formed is taken up before cooling in 2.5 liters of boiling ethyl acetate and the solution filtered. On cooling the filtrate 1.1 kg (83% of theory) of 2-amino-4'-(diethylamino)-2'- methylbenzanilide precipitates out. After re-crystallzation from n-propanol the colorless crystalline product obtained melts at 152°C.
Therapeutic FunctionAnticonvulsant
Atolide Preparation Products And Raw materials
Raw materialsIsatoic Anhydride-->4-(N,N-Diethyl)-2-methyl-p-phenylenediamine monohydrochloride
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Atolide