Antiepileptic and anticonvulsant

Anticonvulsants are clinically used in children with high fever, eclampsia, tetanus, grand mal seizures, and excessive central excitation caused by certain medicine. With a strong inhibitory effect on the central nervous system, they are a class of drugs that can remit or relieve the symptoms of seizures and used in the treatment of convulsions caused by various effects, such as eclampsia, tetanus, grand mal seizures and central stimulant poisoning. Barbiturates such as phenobarbital, benzodiazepines such as clozapine, diazepam, nitrazepam and chloral hydrate, dilantin, magnesium sulfate injection are commonly used anticovulsants.

Epilepsy is a chronic, reduplicative, paroxysmal central nervous system disease, characterized by the sudden abnormal bursts of high-frequency discharge of brain nerves and the sequential spread to the surrounding. Antiepileptics belong to anticonvulsants, used for the treatment of epilepsy. Antiepileptic drug is a symptomatic treatment for pilepsy patients to control the symptoms, so the patients must accept long-term medication. Antiepileptics stop seizures in two ways, in one of which they directly act on the brain tissue local epilepsy lesions, reducing the excessive discharge; in the other of which they act on the normal brain tissue around the lesion to prevent the spread of abnormal discharge. Phenytoin, phenobarbital, deoxybenzene, ethosuximide, carbamazepine, sodium valproate and benzodiazepines are commonly used antiepileptics.

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Structure Chemical Name CAS MF
Lacosamide Lacosamide 175481-36-4 C13H18N2O3
Levetiracetam Levetiracetam 102767-28-2 C8H14N2O2
2-Propylpentanoic acid 2-Propylpentanoic acid 99-66-1 C8H16O2
Topiramate Topiramate 97240-79-4 C12H21NO8S
Vanillin Vanillin 121-33-5 C8H8O3
Oxcarbazepine Oxcarbazepine 28721-07-5 C15H12N2O2
Zonisamide Zonisamide 68291-97-4 C8H8N2O3S
Carbamazepine Carbamazepine 298-46-4 C15H12N2O
Piperine Piperine 94-62-2 C17H19NO3
Pregabalin Pregabalin 148553-50-8 C8H17NO2
Riluzole Riluzole 1744-22-5 C8H5F3N2OS
Gabapentin Gabapentin 60142-96-3 C9H17NO2
5,5-Diphenylhydantoin 5,5-Diphenylhydantoin 57-41-0 C15H12N2O2
Phenytoin sodium Phenytoin sodium 630-93-3 C15H13N2NaO2
YKP-3089 YKP-3089 913088-80-9 C10H10ClN5O2
2-AMINO-N-(1-METHYL-1,2-DIPHENYLETHYL)ACETAMIDE HYDROCHLORIDE 2-AMINO-N-(1-METHYL-1,2-DIPHENYLETHYL)ACETAMIDE HYDROCHLORIDE 111686-79-4 C17H21ClN2O
PeraMpanel PeraMpanel 380917-97-5 C23H15N3O
2-(2-CHLOROPHENYL)-2-HYDROXYETHYL CARBAMATE 2-(2-CHLOROPHENYL)-2-HYDROXYETHYL CARBAMATE 194085-75-1 C813CH8D2Cl15NO3
Tezampanel hydrate Tezampanel hydrate 317819-68-4 C13H23N5O3
perampanel 3/4 hydrate perampanel 3/4 hydrate 1571982-04-1 C23H17N3O2
TERT-BUTYL-BICYCLO [2.2.2] TERT-BUTYL-BICYCLO [2.2.2] 70636-86-1 C8H15O3PS
Nabazenil Nabazenil 58019-65-1 C35H55NO3
Fluzinamide Fluzinamide 76263-13-3 C12H13F3N2O2
Bexicaserin Bexicaserin 2035818-24-5 C15H19F2N3O
N-[(acetylamino)carbonyl]-2-phenylbutanamide N-[(acetylamino)carbonyl]-2-phenylbutanamide 13402-08-9 C13H16N2O3
Buramate Buramate 4663-83-6 C10H13NO3
Citenamide Citenamide 10423-37-7 C16H13NO
Tolgabide Tolgabide 86914-11-6
sabeluzole sabeluzole 104383-17-7 C22H26FN3O2S
2,6-DIAMINO-3-(2,3,5-TRICHLOROPHENYL)-PYRAZINE 2,6-DIAMINO-3-(2,3,5-TRICHLOROPHENYL)-PYRAZINE 212778-82-0 C10H7Cl3N4
Setmelanotide Setmelanotide 1294000-61-5 C14H14ClF5N4O2S
ACT 709478 ACT 709478 1838651-58-3 C22H18F3N5O
METHARBITAL CIII (200 MG) METHARBITAL CIII (200 MG) 50-11-3 C9H14N2O3
barbexaclone barbexaclone 4388-82-3 C12H12N2O3.C10H21N
Caffeine Citrate Caffeine Citrate 93390-81-9 C16H15N2O6P
Albutoin Albutoin 830-89-7 C10H16N2OS
Ilepcimide Ilepcimide 82857-82-7 C15H17NO3
Soticlestat Soticlestat 1429505-03-2 C23H23N3O2
1-Piperazinecarboxylic acid, 2-methyl-4-[[3-(trifluoromethoxy)phenyl]methyl]-, 5-(aminocarbonyl)-3-pyridinyl ester, (2R)- 1-Piperazinecarboxylic acid, 2-methyl-4-[[3-(trifluoromethoxy)phenyl]methyl]-, 5-(aminocarbonyl)-3-pyridinyl ester, (2R)- 2244136-58-9 C20H21F3N4O4
PF-06372865 PF-06372865 1614245-70-3 C22H21FN4O3S
(Z)-1-(2-Chloro-2-(2,4-dichlorophenyl)ethenyl)-(1H)-1,2,4-triazolehydrochloride (Z)-1-(2-Chloro-2-(2,4-dichlorophenyl)ethenyl)-(1H)-1,2,4-triazolehydrochloride 117857-45-1 C10H6Cl3N3
Ralitoline Ralitoline 93738-40-0
ameltolide ameltolide 787-93-9 C15H16N2O
Milacemide hydrochloride [USAN] Milacemide hydrochloride [USAN] 76990-85-7 C7H17ClN2O
Zoniclezole hydrochloride Zoniclezole hydrochloride 121929-46-2 C12H11Cl2N3O
NBI-921352 NBI-921352 2154406-04-7 C22H25FN4O2S2
Fenasi Fenasi
CYHEPTAMIDE CYHEPTAMIDE 7199-29-3 C16H15NO
dezinamide dezinamide 91077-32-6 C11H11F3N2O2
Atolide Atolide 16231-75-7 C18H23N3O
Methetoin Methetoin 5696-06-0 C12H14N2O2
Nafimidone Nafimidone 70891-37-1 C15H12N2O.ClH
Ropizine Ropizine 3601-19-2 C24H26N4
Tiagabine Tiagabine 115103-54-3 C20H25NO2S2
Mephenytoin Mephenytoin 50-12-4 C12H14N2O2
ETHOTOIN ETHOTOIN 86-35-1 C11H12N2O2
MAGNESIUM DIPROPYLACETATE HYDRATE MAGNESIUM DIPROPYLACETATE HYDRATE 62959-43-7 C16H30MgO4
Primidone Primidone 125-33-7 C12H14N2O2
VIGABATRIN VIGABATRIN 60643-86-9 C6H11NO2
Progabide Progabide 62666-20-0 C17H16ClFN2O2
ETHOSUXIMIDE ETHOSUXIMIDE 77-67-8 C7H11NO2
fluoresone fluoresone 2924-67-6 C8H9FO2S
PHENYLACETYLUREA PHENYLACETYLUREA 63-98-9 C9H10N2O2
METHSUXIMIDE METHSUXIMIDE 77-41-8 C12H13NO2
3,5,5-TRIMETHYLOXAZOLIDINE-2,4-DIONE 3,5,5-TRIMETHYLOXAZOLIDINE-2,4-DIONE 127-48-0 C6H9NO3
PHENSUXIMIDE PHENSUXIMIDE 86-34-0 C11H11NO2
Seletracetam Seletracetam 357336-74-4 C10H14F2N2O2
Lamotrigine Lamotrigine 84057-84-1 C9H7Cl2N5
Sodium 2-propylpentanoate Sodium 2-propylpentanoate 1069-66-5 C8H15NaO2
Valpromide Valpromide 2430-27-5 C8H17NO
Eterobarb Eterobarb 27511-99-5 C16H20N2O5
piperine piperine 7780-20-3 C17H19NO3
Felbamate Felbamate 25451-15-4 C11H14N2O4
doxenitoin doxenitoin 3254-93-1 C15H14N2O
PARAMETHADIONE (500 MG) PARAMETHADIONE (500 MG) 115-67-3 C7H11NO3
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