Vatanidipine manufacturers
- Vatanidipine
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- $197.00
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2026-05-11
- CAS:116308-55-5
- Purity: 99.95%
- Supply Ability: 10g
- Vatanidipine
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- $1.00
-
2019-12-27
- CAS:116308-55-5
- Min. Order: 1KG
- Purity: 97%-99.9%
- Supply Ability: 100kg
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| | Vatanidipine Basic information |
| Product Name: | Vatanidipine | | Synonyms: | Vatanidipine;AE0047;2,6-Dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylic acid 3-[4-(4-benzhydryl-1-piperazinyl)phenethyl]5-methyl ester;2,6-Dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylic acid 3-methyl 5-[2-[4-[(4-benzhydrylpiperazin)-1-yl]phenyl]ethyl] ester;Watanidipine;WATA-012;3,5-Pyridinedicarboxylic acid, 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-, 3-[2-[4-[4-(diphenylmethyl)-1-piperazinyl]phenyl]ethyl] 5-methyl ester;Vatanidipine, 10 mM in DMSO | | CAS: | 116308-55-5 | | MF: | C41H42N4O6 | | MW: | 686.805 | | EINECS: | | | Product Categories: | | | Mol File: | 116308-55-5.mol |  |
| | Vatanidipine Chemical Properties |
| Boiling point | 799.4±60.0 °C(Predicted) | | density | 1.237±0.06 g/cm3(Predicted) | | pka | 7.11±0.10(Predicted) |
| | Vatanidipine Usage And Synthesis |
| Uses | Vatanidipine (Watanidipine) is an orally active dihydropyridine (DHP)-type calcium channel blocker and a useful antihypertensive agent. Vatanidipine shows vasodilatory effects and also suppresses noradrenaline release from sympathetic nerve endings[1][2]. | | in vivo | Vatanidipine (1-10 mg/kg, p.o.) suppresses the systolic blood pressure of spontaneously hypertensive rats[1].
| | References | [1] Matsumura Y, et al. Vatanidipine hydrochloride: a new long-lasting antihypertensive agent. Expert Opin Investig Drugs. 2001 Jan;10(1):139-55. DOI:10.1517/13543784.10.1.139
[2] H Shinyama, et al. Effects of the calcium antagonist AE0047 on the development of neurological deficit and infarction after middle cerebral artery occlusion in stroke-prone spontaneously hypertensive rats. J Pharm Pharmacol. 1997 Sep;49(9):919-24. DOI:10.1111/j.2042-7158.1997.tb06136.x |
| | Vatanidipine Preparation Products And Raw materials |
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