1H-Indole-1-butanoic acid, 4-[5-[5-chloro-6-(1-methylethoxy)-3-pyridinyl]-1,2,4-oxadiazol-3-yl]-, hydrochloride (1:1) manufacturers
- GSK2018682 HCl
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- $1520.00
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2026-04-20
- CAS:1034687-52-9
- Purity:
- Supply Ability: 10g
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| | 1H-Indole-1-butanoic acid, 4-[5-[5-chloro-6-(1-methylethoxy)-3-pyridinyl]-1,2,4-oxadiazol-3-yl]-, hydrochloride (1:1) Basic information |
| | 1H-Indole-1-butanoic acid, 4-[5-[5-chloro-6-(1-methylethoxy)-3-pyridinyl]-1,2,4-oxadiazol-3-yl]-, hydrochloride (1:1) Chemical Properties |
| | 1H-Indole-1-butanoic acid, 4-[5-[5-chloro-6-(1-methylethoxy)-3-pyridinyl]-1,2,4-oxadiazol-3-yl]-, hydrochloride (1:1) Usage And Synthesis |
| Uses | GSK2018682 hydrochloride is an agonist for S1P1 and S1P5 receptor with pEC50s of 7.7 and 7.2, respectively, and has no agonist activity towards human S1P2, S1P3, or S1P4. GSK2018682 hydrochloride is used in the research of multiple sclerosis. | | References | [1] Xu J, et al. Safety, pharmacokinetics, pharmacodynamics, and bioavailability of GSK2018682, a sphingosine-1-phosphate receptor modulator, in healthy volunteers. Clin Pharmacol Drug Dev. 2014 May;3(3):170-8. DOI:10.1002/cpdd.98 |
| | 1H-Indole-1-butanoic acid, 4-[5-[5-chloro-6-(1-methylethoxy)-3-pyridinyl]-1,2,4-oxadiazol-3-yl]-, hydrochloride (1:1) Preparation Products And Raw materials |
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