NS-3736 manufacturers
- NS-3736
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- $1520.00
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2026-04-20
- CAS:265646-94-4
- Purity:
- Supply Ability: 10g
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| | NS-3736 Basic information |
| Product Name: | NS-3736 | | Synonyms: | NS-3736;N-[4-Bromo-2-(2H-tetrazol-5-yl)phenyl]-N′-[4-chloro-3-(trifluoromethyl)phenyl]urea | | CAS: | 265646-94-4 | | MF: | C15H9BrClF3N6O | | MW: | 461.62 | | EINECS: | | | Product Categories: | | | Mol File: | 265646-94-4.mol |  |
| | NS-3736 Chemical Properties |
| density | 1.811±0.06 g/cm3(Temp: 20 °C; Press: 760 Torr)(Predicted) | | pka | 3.94±0.10(Predicted) |
| | NS-3736 Usage And Synthesis |
| Uses | NS3736 is an orally effective chloride channel inhibitor that can be used for the research of osteoporosis. NS3736 targets the CIC-7 channel in osteocytes, blocks osteoclast acidification and resorption in vitro, with IC50=30 μM. In a rat model of ovariectomy-induced osteoporosis, NS3736 can enhance bone strength and bone density[1]. | | References | [1] Schaller S, et al. The chloride channel inhibitor NS3736 [corrected] prevents bone resorption in ovariectomized rats without changing bone formation. J Bone Miner Res. 2004 Jul;19(7):1144-53. DOI:10.1359/JBMR.040302 |
| | NS-3736 Preparation Products And Raw materials |
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Tag:NS-3736(265646-94-4)
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