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| | chaparrinone Basic information |
| Product Name: | chaparrinone | | Synonyms: | chaparrinone;Picras-3-ene-2,16-dione, 11,20-epoxy-1,11,12-trihydroxy-, (1β,11β,12α)- | | CAS: | 22611-34-3 | | MF: | C20H26O7 | | MW: | 378.42 | | EINECS: | | | Product Categories: | | | Mol File: | 22611-34-3.mol |  |
| | chaparrinone Chemical Properties |
| Melting point | 238-242 °C | | Boiling point | 626.1±55.0 °C(Predicted) | | density | 1.45±0.1 g/cm3(Predicted) | | pka | 12.03±0.70(Predicted) |
| | chaparrinone Usage And Synthesis |
| Uses | Chaparrinone is a quassinoid that can be isolated from the root of Eurycoma harmandiana. Chaparrinone has antimalarial and cytotoxic activities against Plasmodium falciparum and P-388 cells (IC50: 0.037 and 0.34 μg/mL respectively)[1][2]. | | Definition | ChEBI: Chaparrinone is a triterpenoid. | | References | [1] Kanchanapoom T, et al. Quassinoids from Eurycoma harmandiana. Phytochemistry. 2001 Aug;57(8):1205-8. DOI:10.1016/s0031-9422(01)00235-7
[2] Franois G, et al. Antimalarial and cytotoxic potential of four quassinoids from Hannoa chlorantha and Hannoa klaineana, and their structure-activity relationships. Int J Parasitol. 1998 Apr;28(4):635-40. DOI:10.1016/s0020-7519(98)00008-3 |
| | chaparrinone Preparation Products And Raw materials |
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