| Company Name: |
Accela ChemBio Inc. |
| Tel: |
+1-858-6993322 +86-18019713315 |
| Email: |
info@accelachem.com |
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| | justicidin A Basic information |
| Product Name: | justicidin A | | Synonyms: | justicidin A;4,6,7-Trimethoxy-9-[3,4-(me;4,6,7-Trimethoxy-9-(1,3-benzodioxol-5-yl)naphtho[2,3-c]furan-1(3H)-one;Naphtho[2,3-c]furan-1(3H)-one, 9-(1,3-benzodioxol-5-yl)-4,6,7-trimethoxy-;Justicidin;Justicidins;9-(Benzo[d][1,3]dioxol-5-yl)-4,6,7-trimethoxynaphtho[2,3-c]furan-1(3H)-one | | CAS: | 25001-57-4 | | MF: | C22H18O7 | | MW: | 394.37 | | EINECS: | | | Product Categories: | | | Mol File: | 25001-57-4.mol |  |
| | justicidin A Chemical Properties |
| Melting point | 263° | | Boiling point | 644.5±55.0 °C(Predicted) | | density | 1.366±0.06 g/cm3(Predicted) | | form | Solid | | color | White to off-white |
| | justicidin A Usage And Synthesis |
| Uses | justicidin A is a nature product that could be isolated form Justicia procumbens. justicidin A decreases the level of Ku70 leading to translocation of Bax from the cytosol to mitochondria to induce apoptosis. justicidin A can be used in research of cancer[1]. | | Definition | ChEBI: Justicidin A is a lignan. | | in vivo | justicidin A (6.2 mg/kg; p.o.; daily, for 56 days) suppresses the growth of human colorectal cancer cells in mice[1]. | Animal Model: | NOD-SCID mice with HT-29 cells xenograftes[1] | | Dosage: | 6.2 mg/kg | | Administration: | Oral administration; daily, for 56 days | | Result: | Inhibited tumor growth and decreased tumor weight. |
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| | justicidin A Preparation Products And Raw materials |
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