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| | 4-Amino-6-chlorobenzene-1,3-disulfonamide Basic information |
| | 4-Amino-6-chlorobenzene-1,3-disulfonamide Chemical Properties |
| Melting point | 257-261 °C(lit.) | | Boiling point | 614.4±65.0 °C(Predicted) | | density | 1.584 (estimate) | | refractive index | 1.6100 (estimate) | | storage temp. | 2-8°C | | solubility | DMSO (Slightly), Methanol (Slightly) | | pka | 9.24±0.60(Predicted) | | form | Powder | | color | White to off-white | | Merck | 14,2076 | | BRN | 1083877 | | InChI | InChI=1S/C6H8ClN3O4S2/c7-3-1-4(8)6(16(10,13)14)2-5(3)15(9,11)12/h1-2H,8H2,(H2,9,11,12)(H2,10,13,14) | | InChIKey | IHJCXVZDYSXXFT-UHFFFAOYSA-N | | SMILES | C1(S(N)(=O)=O)=C(Cl)C=C(N)C(S(N)(=O)=O)=C1 | | CAS DataBase Reference | 121-30-2(CAS DataBase Reference) | | EPA Substance Registry System | 1,3-Benzenedisulfonamide, 4-amino-6-chloro- (121-30-2) |
| | 4-Amino-6-chlorobenzene-1,3-disulfonamide Usage And Synthesis |
| Description | 4-Amino-6-chlorobenzene-1,3-disulfonamide is obtained by treating the chloride with ammonia in tert-butanol and concentrating the solution by evaporation; the yield is 80 %. Condensation with formic acid gives 6-chloro-7-sulfamoyl-1,2,4-benzothiadiazine 1,1-dioxide, an important diuretic. | | Chemical Properties | Light Brown Solid | | Uses | Diuretic. | | Uses | 4-Amino-6-chloro-1,3-benzenedisulfonamide was used in the synthesis of deuterated thiazides by undergoing condensation with appropriately labeled aldehydes. | | Definition | ChEBI: Chloraminophenamide is a sulfonamide. | | General Description | Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards. |
| | 4-Amino-6-chlorobenzene-1,3-disulfonamide Preparation Products And Raw materials |
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