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| | 2,3,4,4'-Tetrahydroxybenzophenone Basic information |
| Product Name: | 2,3,4,4'-Tetrahydroxybenzophenone | | Synonyms: | 4-(4-Hydroxybenzoyl)-1,2,3-trihydroxybenzene;2,3,4,4-TETRAHYDROXYBENZOPHENONE;2,3,4,4'-THBP;2,3,4,4'-Tetrehydroxybenzophenone;(4-hydroxyphenyl)(2,3,4-trihydroxyphenyl) methanone;2,3,4,4'-Tetrahydroxybenzophenone(Bp-28);Methanone, (4-hydroxyphenyl)(2,3,4-trihydroxyphenyl)-;2,3,4,4'-Tetraanhydroxybenzophenone | | CAS: | 31127-54-5 | | MF: | C13H10O5 | | MW: | 246.22 | | EINECS: | 202-110-6 | | Product Categories: | Aromatic Benzophenones & Derivatives (substituted);RAW material for Photo Active Compounds;Industrial/Fine Chemicals | | Mol File: | 31127-54-5.mol |  |
| | 2,3,4,4'-Tetrahydroxybenzophenone Chemical Properties |
| Melting point | 199-204°C | | Boiling point | 519.0±50.0 °C(Predicted) | | density | 1.526±0.06 g/cm3(Predicted) | | storage temp. | Sealed in dry,Room Temperature | | pka | 7.38±0.40(Predicted) | | form | powder to crystal | | color | Light yellow to Amber to Dark green | | Water Solubility | 15.07g/L(24.99 ºC) | | InChI | InChI=1S/C13H10O5/c14-8-3-1-7(2-4-8)11(16)9-5-6-10(15)13(18)12(9)17/h1-6,14-15,17-18H | | InChIKey | ZRDYULMDEGRWRC-UHFFFAOYSA-N | | SMILES | C(C1=CC=C(O)C=C1)(C1=CC=C(O)C(O)=C1O)=O | | CAS DataBase Reference | 31127-54-5(CAS DataBase Reference) |
| | 2,3,4,4'-Tetrahydroxybenzophenone Usage And Synthesis |
| Chemical Properties | Yellow powder | | Uses | 2,3,4,4'-Tetrahydroxybenzophenone can be used for positive resist composition. | | Preparation | Preparation by benzoylation of pyrogallol with p-hydroxybenzoic acid in the presence of Amberlyst-15 in refluxing toluene for 21 h under azeotropical removal of water (86%). | | Synthesis | General procedure for the synthesis of (4-hydroxyphenyl)(2,3,4-trihydroxyphenyl)methanone from o-hydroxybenzenetriol and p-hydroxybenzoic acid: 0.11 moles of p-hydroxybenzoic acid and 0.1 moles of pyrophosphoric acid as an acylating agent as well as 0.015 moles of concentrated sulfuric acid were added in a reactor and mixed well. An inert gas was passed for 10 minutes to remove air. After increasing the system temperature to 70-80°C, the reactor was closed, the temperature was adjusted to 110-130°C, the pressure was maintained at 0.1-5 MPa and the reaction was carried out for 3 hours. Upon completion of the reaction, the reaction mixture was cooled to 50-60 °C and held at this temperature for 1.5 hours. Subsequently, 200 ml of 20% ethanol solution was added and crystallized at 0-5°C. The crystals were collected by filtration and dried to give the target product (4-hydroxyphenyl)(2,3,4-trihydroxyphenyl)methanone. The molar yield of this step was 78.16% and the purity was ≥98.5% by HPLC. | | References | [1] Patent: CN106349036, 2017, A. Location in patent: Paragraph 0032-0037
[2] Patent: CN106365961, 2017, A. Location in patent: Paragraph 0030; 0031; 0032; 0033; 0034; 0035
[3] Fortschr. Teerfarbenfabr. Verw. Industriezweige, vol. 2, p. 482
[4] Fortschr. Teerfarbenfabr. Verw. Industriezweige, vol. 2, p. 483 |
| | 2,3,4,4'-Tetrahydroxybenzophenone Preparation Products And Raw materials |
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