SUBSTANCE P (4-11) manufacturers
- SUBSTANCE P (4-11)
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2025-04-04
- CAS:53749-60-3
- Min. Order: 1kg
- Purity: 98%
- Supply Ability: 1Ton
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| | SUBSTANCE P (4-11) Basic information |
| Product Name: | SUBSTANCE P (4-11) | | Synonyms: | SUBSTANCE P (4-11);SUBSTANCE P(4-11), [D-PRO4, D-TRP7,9];OCTA-SUBSTANCE P;PRO-GLN-GLN-PHE-PHE-GLY-LEU-MET-NH2;substance P fragment 4-11 acetate;Substance-P-(4-11)Octa-Substance P;H-PRO-GLN-GLN-PHE-PHE-GLY-LEU-MET-NH2;(2S)-N-[(1S)-1-[[(1S)-1-[[1-[[(1S)-1-carbamoyl-3-methylsulfanyl-propyl]carbamoyl]-3-methyl-butyl]carbamoylmethylcarbamoyl]-2-phenyl-ethyl]carbamoyl]-2-phenyl-ethyl]-2-[[(2S)-4-carbamoyl-2-(pyrrolidine-2-carbonylamino)butanoyl]amino]pentanediamide | | CAS: | 53749-60-3 | | MF: | C46H67N11O10S | | MW: | 966.16 | | EINECS: | | | Product Categories: | | | Mol File: | 53749-60-3.mol |  |
| | SUBSTANCE P (4-11) Chemical Properties |
| Boiling point | 1470.114±65.00 °C(Press: 760.00 Torr)(predicted) | | density | 1.266±0.06 g/cm3(Temp: 25 °C; Press: 760 Torr)(predicted) | | storage temp. | −20°C | | pka | 13.264±0.46(predicted) |
| | SUBSTANCE P (4-11) Usage And Synthesis |
| Uses | Substance P (4-11), the C-terminus fragment of Substance P (Substance P (HY-P0201)), is a Substance P agonist that shows highly selective for NK1 receptors[1][2]. | | References | [1] D G Payan, et al. Specific stimulation of human T lymphocytes by substance P. J Immunol. 1983 Oct;131(4):1613-5. PMID:6194207
[2] L Wang, et al. Substance P induces ion secretion in mouse small intestine through effects on enteric nerves and mast cells. Am J Physiol. 1995 Jul;269(1 Pt 1):G85-92. DOI:10.1152/ajpgi.1995.269.1.G85
[3] P Cornaglia-Ferraris, et al. Sensory neuropeptides (substance P) and 4-11 SP enhance human neutrophils chemiluminescence; the role of L-arginine. Int J Immunopharmacol. 1986;8(4):463-8. DOI:10.1016/0192-0561(86)90133-5 |
| | SUBSTANCE P (4-11) Preparation Products And Raw materials |
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