6-(4-Methoxyphenyl)furo[2,3-d]pyrimidin-4-amine

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Company Name: Shanghai YuanYe Biotechnology Co., Ltd.  
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6-(4-Methoxyphenyl)furo[2,3-d]pyrimidin-4-amine manufacturers

6-(4-Methoxyphenyl)furo[2,3-d]pyrimidin-4-amine Basic information
Product Name:6-(4-Methoxyphenyl)furo[2,3-d]pyrimidin-4-amine
Synonyms:6-(4-methoxy-phenyl)-furo[2,3-d]pyrimidin-4-ylamine;Kinase IN-1;TIE-2/VEGFR-2 kinase-IN-1;Furo[2,3-d]pyrimidin-4-amine, 6-(4-methoxyphenyl)-;6-(4-Methoxyphenyl)furo[2,3-d]pyrimidin-4-amine
CAS:453590-24-4
MF:C13H11N3O2
MW:241.25
EINECS:
Product Categories:
Mol File:453590-24-4.mol
6-(4-Methoxyphenyl)furo[2,3-d]pyrimidin-4-amine Structure
6-(4-Methoxyphenyl)furo[2,3-d]pyrimidin-4-amine Chemical Properties
Boiling point 450.4±45.0 °C(Predicted)
density 1.308±0.06 g/cm3(Predicted)
storage temp. Store at -20°C
solubility DMSO: 5 mg/mL (20.73 mM; ultrasonic and warming and heat to 80°C)
form Solid
pka4.73±0.40(Predicted)
color Yellow to brown
Safety Information
MSDS Information
6-(4-Methoxyphenyl)furo[2,3-d]pyrimidin-4-amine Usage And Synthesis
UsesTIE-2/VEGFR-2 kinase-IN-1 is used for the synthesis of TIE-2 and/or VEGFR-2 inhibitors, extracted from patent WO2003022852, example 14. TIE-2/VEGFR-2 kinase-IN-1 is used for the study of diseases associated with inappropriate angiogenesis[1].
IC 50Tie2
References[1] Jerry Leroy Adams, et al. Furo-and thienopyrimidine derivatives as angiogenesis inhibitors. Patent WO2003022852.
6-(4-Methoxyphenyl)furo[2,3-d]pyrimidin-4-amine Preparation Products And Raw materials
Tag:6-(4-Methoxyphenyl)furo[2,3-d]pyrimidin-4-amine(453590-24-4) Related Product Information
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