| Company Name: |
3B Pharmachem (Wuhan) International Co.,Ltd.
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| Tel: |
821-50328103-801 18930552037 |
| Email: |
3bsc@sina.com |
| Products Intro: |
Product Name:Cinanserin hydrochloride;N-[2-[[3-(DiMethylaMino)propyl]thio]phenyl]-3-phenyl-2-propenaMidehydrochloride
CAS:1166-34-3
Purity:99% HPLC Package:1Mg ; 5Mg;10Mg ;100Mg;250Mg ;500Mg ;1g;2.5g ;5g ;10g
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| Company Name: |
BOC Sciences
|
| Tel: |
1-631-485-4226; 16314854226 |
| Email: |
info@bocsci.com |
| Products Intro: |
Product Name:Cinanserin
CAS:1166-34-3
Purity:>99 % Remarks:Reach out to us for more information about custom solutions.
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CINANSERIN HYDROCHLORIDE manufacturers
- Cinanserin
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- $2500.00 / 100mg
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2026-01-05
- CAS:1166-34-3
- Min. Order:
- Purity:
- Supply Ability: 10g
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| | CINANSERIN HYDROCHLORIDE Basic information |
| Product Name: | CINANSERIN HYDROCHLORIDE | | Synonyms: | N-[2-[[3-(DIMETHYLAMINO)PROPYL]THIO]PHENYL]-3-PHENYL-2-PROPENAMIDE;N-[2-[[3-(DIMETHYLAMINO)PROPYL]THIO]PHENYL]-3-PHENYL-2-PROPENAMIDE HYDROCHLORIDE;2'-(3-DIMETHYLAMINOPROPYL-THIO)-CINNAMANILIDE HYDROCHLORIDE;CINANSERIN;CINANSERIN HYDROCHLORIDE;DPTC;DPTC HYDROCHLORIDE;Cinanserine | | CAS: | 1166-34-3 | | MF: | C20H24N2OS | | MW: | 340.48 | | EINECS: | | | Product Categories: | Serotonin receptor | | Mol File: | 1166-34-3.mol |  |
| | CINANSERIN HYDROCHLORIDE Chemical Properties |
| Melting point | 82-83 °C | | Boiling point | 519.5±50.0 °C(Predicted) | | density | 1.13±0.1 g/cm3(Predicted) | | RTECS | UC6323000 | | storage temp. | Desiccate at RT | | solubility | Chloroform (Slightly), Methanol (Slightly) | | pka | 13.46±0.70(Predicted) | | form | Solid | | color | White to Off-White | | Water Solubility | Soluble to 50 mM in water |
| | CINANSERIN HYDROCHLORIDE Usage And Synthesis |
| Uses | Serotonin
inhibitor. | | Uses | A 5-HT antagonist | | Definition | ChEBI: Cinanserin is an aryl sulfide that is (2E)-3-phenyl-N-(2-sulfanylphenyl)prop-2-enamide in which the hydrogen of the thiol group is substituted by a 3-(dimethylamino)propyl group. It is a 5-hydroxytryptamine receptor antagonist and an inhibitor of SARS-CoV replication. It has a role as an EC 3.4.22.69 (SARS coronavirus main proteinase) inhibitor, an antiviral agent and an anticoronaviral agent. It is a tertiary amino compound, a secondary carboxamide, a member of cinnamamides and an aryl sulfide. It is a conjugate base of a cinanserin(1+). | | Biological Activity | 5-HT 2 antagonist. | | in vivo | Cinanserin (5 mg/kg; i.v.) treatment significantly reduces systemic burn edema levels[1]. | Animal Model: | Male Wistar rats (250 g) underwent thermal injury[1] | | Dosage: | 5 mg/kg | | Administration: | Intravenous injection; for 2 hours | | Result: | Significantly reduced systemic burn edema to shamburn levels, leukocyte-endothelial interactions are significantly reduced by administration of Cinanserin. |
| | IC 50 | 5-HT2 Receptor: 41 nM (Ki); 5-HT1 Receptor: 3500 nM (Ki); SARS-CoV 3CLpro: 49.4 μM (Kd) |
| | CINANSERIN HYDROCHLORIDE Preparation Products And Raw materials |
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