Cinanserin hydrochloride manufacturers
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| | Cinanserin hydrochloride Basic information |
| Product Name: | Cinanserin hydrochloride | | Synonyms: | 2'-(3-DIMETHYLAMINOPROPYL-THIO)-CINNAMANILIDE HYDROCHLORIDE;N-[2-[[3-(DIMETHYLAMINO)PROPYL]THIO]PHENYL]-3-PHENYL-2-PROPENAMIDE;N-[2-[[3-(DIMETHYLAMINO)PROPYL]THIO]PHENYL]-3-PHENYL-2-PROPENAMIDE HYDROCHLORIDE;2’-((3-(dimethylamino)propyl)thio)-cinnamanilidmonohydrochloride;maptc;n-(2-((3-(dimethylamino)propyl)thio)phenyl)-3-phenyl-2-propenamidmonohyd;sq10,643;DPTC 2'-(3-Dimethylaminopropylthio)cinnamanilide hydrochloride | | CAS: | 54-84-2 | | MF: | C20H25ClN2OS | | MW: | 376.95 | | EINECS: | | | Product Categories: | amino | | Mol File: | 54-84-2.mol |  |
| | Cinanserin hydrochloride Chemical Properties |
| density | 1.22 g/cm3 | | storage temp. | Inert atmosphere,Store in freezer, under -20°C | | solubility | DMSO : 125 mg/mL (331.62 mM; Need ultrasonic) | | form | Powder | | color | Light yellow to yellow | | Water Solubility | Soluble to 50 mM in water |
| | Cinanserin hydrochloride Usage And Synthesis |
| Uses | Serotonin
inhibitor. | | Application | Cinanserin Hydrochloride is a useful research chemical. Cinanserin is an inhibitor of 3C-like proteinase of severe acute respiratory syndrome coronavirus and strongly reduces virus replication in vitro. | | Definition | ChEBI: Cinanserin hydrochloride is the hydrochloride salt of cinanserin. It is an inhibitor of 3C-like proteinase of severe acute respiratory syndrome coronavirus (SARS-Cov) and reduces virus replication in vitro. It has a role as an antiviral agent, an EC 3.4.22.69 (SARS coronavirus main proteinase) inhibitor and an anticoronaviral agent. It contains a cinanserin(1+). | | in vivo | Cinanserin (5 mg/kg; intravenous injection; for 2 hours; male Wistar rats) treatment significantly reduces systemic burn edema to shamburn levels. Leukocyte-endothelial interactions are significantly reduced by administration of Cinanserin[2]. | Animal Model: | Male Wistar rats (250 g) underwent thermal injury[2] | | Dosage: | 5 mg/kg | | Administration: | Intravenous injection; for 2 hours | | Result: | Significantly reduced systemic burn edema to shamburn levels..
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| | IC 50 | 5-HT2 Receptor: 41 nM (Ki); 3C-like proteinase | | storage | Desiccate at RT |
| | Cinanserin hydrochloride Preparation Products And Raw materials |
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