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BOC Sciences
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Product Name:I2906
CAS:331963-29-2
Purity:>98% Remarks:Reach out to us for more information about custom solutions.
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| Company Name: |
Haoyuan Chemexpress Co., Ltd.
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021-58950125 |
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info@chemexpress.com |
| Products Intro: |
Product Name:I2906
CAS:331963-29-2
Purity:>98% Package:1042RMB/100mg
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| Company Name: |
AdooQ BioScience, LLC
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+1 (866) 930-6790 |
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info@adooq.com |
| Products Intro: |
Product Name:I2906
CAS:331963-29-2
Purity:98% Package:5mg;10mg;25mg;50mg;100mg;250mg;500mg;1g
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I2906 manufacturers
- I2906
-
- $29.00
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2026-05-11
- CAS:331963-29-2
- Purity: 99.92%
- Supply Ability: 10g
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| Product Name: | I2906 | | Synonyms: | I-2906
(I 2906;I2906;1-Ethyl-1,2-dihydro-4-hydroxy-2-oxo-3-quinolinecarboxylic acid 2-(1-oxotridecyl)hydrazide;3-Quinolinecarboxylic acid, 1-ethyl-1,2-dihydro-4-hydroxy-2-oxo-, 2-(1-oxotridecyl)hydrazide;1-ET-4-HO-2-OXO-1,2-DIHYDRO-QUINOLINE-3-CARBOXYLIC ACID N'-TRIDECANOYL-HYDRAZIDE;1-ET-4-HO-2-OXO-1,2-DIHYDRO-QUINOLINE-3-CARBOXYLIC ACID N'-TRIDECANOYL-HYDRAZIDE | | CAS: | 331963-29-2 | | MF: | C25H37N3O4 | | MW: | 443.58 | | EINECS: | | | Product Categories: | | | Mol File: | 331963-29-2.mol |  |
| | I2906 Chemical Properties |
| Boiling point | 623.9±55.0 °C(Predicted) | | density | 1.132±0.06 g/cm3(Predicted) | | storage temp. | Store at -20°C | | solubility | Soluble in DMSO | | form | Powder | | pka | 4.50±1.00(Predicted) | | color | White to off-white |
| | I2906 Usage And Synthesis |
| Uses | I2906 showed antimycobacterial and cytotoxic activity against mycobacterium tuberculosis.
IC50 Value:
Target: Antibacterial
Under in vitro conditions, I2906 showed excellent antimycobacterial activities and low cytotoxicity. In a murine model infected with M. tuberculosis H37Rv, the reductions on bacterial loads of both lungs and spleen were statistically significant (p < 0.05) between I2906-treated mice and untreated controls after 4 weeks. Further, the colony-forming unit counts in the lungs were dramatically lower (p < 0.05) than that of isoniazid-treated mice by the addition of I2906 after 8 weeks. Moreover, survival rate was increased by I2906 treatment. For multidrug-resistant strain infection, bacterial counts were reduced significantly in the lungs and spleen due to I2906 treatment in comparison with data from untreated controls (p < 0.05). | | References | [1] Lu, Jingning; Yue, Jun; Wu, Jing et al. In vitro and in vivo Activities of a New Lead Compound I2906 against Mycobacterium tuberculosis. Pharmacology (2010), 85(6), 365-371. DOI:10.1159/000299795 |
| | I2906 Preparation Products And Raw materials |
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