(Z)-Butylidenephthalide manufacturers
|
| | (Z)-Butylidenephthalide Basic information |
| Product Name: | (Z)-Butylidenephthalide | | Synonyms: | (Z)-Butylidenephthalide;cis-Butylidenephthalide;(3Z)-3-butylidene-2-benzofuran-1-one;1(3H)-Isobenzofuranone, 3-butylidene-, (3Z)-;(Z)-Butylidenephthalide USP/EP/BP;(Z)-Butylidenephthalide, 10 mM in DMSO | | CAS: | 72917-31-8 | | MF: | C12H12O2 | | MW: | 188.22 | | EINECS: | | | Product Categories: | | | Mol File: | 72917-31-8.mol |  |
| | (Z)-Butylidenephthalide Chemical Properties |
| Boiling point | 200℃ (1.5 Torr) | | density | 1.204±0.06 g/cm3(Predicted) | | solubility | Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. | | form | Oil | | color | Colorless to light yellow | | LogP | 3.723 (est) |
| | (Z)-Butylidenephthalide Usage And Synthesis |
| Uses | (Z)-3-Butylidenephthalide is an antihyperglycemic agent by inhibiting the activity of intestinal and yeast R-glucosidases (IC50=2.35 mM; Ki=4.86 mM)[1]. | | Definition | ChEBI: (Z)-3-butylidenephthalide is a gamma-lactone that is phthalide substituted by a butylidene group at position 3. Isolated from Ligusticum porteri, it exhibits hypoglycemic activity. It has a role as a metabolite, a hypoglycemic agent and an EC 3.2.1.20 (alpha-glucosidase) inhibitor. It is a member of 2-benzofurans and a gamma-lactone. It is functionally related to a 2-benzofuran-1(3H)-one. | | target | PKC | | References | [1] Fernando Brindis, et al. (Z)-3-butylidenephthalide from Ligusticum porteri , an α-glucosidase inhibitor. J Nat Prod. 2011 Mar 25;74(3):314-20. DOI:10.1021/np100447a |
| | (Z)-Butylidenephthalide Preparation Products And Raw materials |
|