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| | N-lauroyl-1-deoxysphingosine (M18:1/12:0) Basic information |
| Product Name: | N-lauroyl-1-deoxysphingosine (M18:1/12:0) | | Synonyms: | N-lauroyl-1-deoxysphingosine (M18:1/12:0);N-C12-deoxysphingosine;N-LAUROYL-1-DEOXYSPHINGOSINE (M18:1/12:0);N-C12-DEOXYSPHINGOSINE;C12 1-Deoxyceramide (m18:1/12:0);Dodecanamide, N-[(1S,2R,3E)-2-hydroxy-1-methyl-3-heptadecen-1-yl]-;N-lauroyl-1-deoxysphingosine (M18 | | CAS: | 1246298-54-3 | | MF: | C30H59NO2 | | MW: | 465.8 | | EINECS: | | | Product Categories: | | | Mol File: | 1246298-54-3.mol |  |
| | N-lauroyl-1-deoxysphingosine (M18:1/12:0) Chemical Properties |
| Boiling point | 597.1±43.0 °C(Predicted) | | density | 0.893±0.06 g/cm3(Predicted) | | storage temp. | -20°C | | solubility | DMF: >20 mg/ml; DMSO: >20 mg/ml; Ethanol: >30 mg/ml; Ethanol:PBS (pH 7.2) (1:1): 0.5 mg/ml; PBS (pH 7.2): <50μg/ml | | form | A crystalline solid | | pka | 13.78±0.20(Predicted) |
| WGK Germany | WGK 3 | | Storage Class | 11 - Combustible Solids |
| | N-lauroyl-1-deoxysphingosine (M18:1/12:0) Usage And Synthesis |
| Description | C12 1-Deoxyceramide (m18:1/12:0) is a medium-chain atypical ceramide containing a 1-deoxysphingosine (m18:1(4E)) backbone. 1-Deoxysphingolipids are formed when serine palmitoyltransferase condenses palmitoyl-CoA with alanine instead of serine during sphingolipid synthesis. | | References | [1] REGULA STEINER. Elucidating the chemical structure of native 1-deoxysphingosine.[J]. Journal of Lipid Research, 2016, 57 7: 1194-1203. DOI: 10.1194/jlr.m067033
[2] I. ALECU. Cytotoxic 1-deoxysphingolipids are metabolized by a cytochrome P450-dependent pathway[S][J]. Journal of Lipid Research, 2016, 58 1: 60-71. DOI: 10.1194/jlr.m072421 |
| | N-lauroyl-1-deoxysphingosine (M18:1/12:0) Preparation Products And Raw materials |
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