ethyl 8-(2-(dimethylamino)ethylamino)-2,3-diphenylpyrido[2,3-b]pyrazin-6-ylcarbamate

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ethyl 8-(2-(dimethylamino)ethylamino)-2,3-diphenylpyrido[2,3-b]pyrazin-6-ylcarbamate manufacturers

  • UNC10217938A
  • UNC10217938A pictures
  • $1298.00
  • 2026-05-11
  • CAS:1347749-97-6
  • Purity:
  • Supply Ability: 10g
  • UNC10217938A
  • UNC10217938A pictures
  • $1298.00
  • 2025-08-22
  • CAS:1347749-97-6
  • Purity:
  • Supply Ability: 10g
ethyl 8-(2-(dimethylamino)ethylamino)-2,3-diphenylpyrido[2,3-b]pyrazin-6-ylcarbamate Basic information
Product Name:ethyl 8-(2-(dimethylamino)ethylamino)-2,3-diphenylpyrido[2,3-b]pyrazin-6-ylcarbamate
Synonyms:ethyl 8-(2-(dimethylamino)ethylamino)-2,3-diphenylpyrido[2,3-b]pyrazin-6-ylcarbamate;UNC10217938A;Carbamic acid, N-[8-[[2-(dimethylamino)ethyl]amino]-2,3-diphenylpyrido[2,3-b]pyrazin-6-yl]-, ethyl ester;UNC-10217938A,UNC10217938A;UNC7938
CAS:1347749-97-6
MF:C26H28N6O2
MW:456.54
EINECS:
Product Categories:
Mol File:1347749-97-6.mol
ethyl 8-(2-(dimethylamino)ethylamino)-2,3-diphenylpyrido[2,3-b]pyrazin-6-ylcarbamate Structure
ethyl 8-(2-(dimethylamino)ethylamino)-2,3-diphenylpyrido[2,3-b]pyrazin-6-ylcarbamate Chemical Properties
Melting point 203-205 °C
Boiling point 581.8±50.0 °C(Predicted)
density 1.247±0.06 g/cm3(Predicted)
pka9.51±0.43(Predicted)
form Solid
color Light yellow to yellow
Safety Information
MSDS Information
ethyl 8-(2-(dimethylamino)ethylamino)-2,3-diphenylpyrido[2,3-b]pyrazin-6-ylcarbamate Usage And Synthesis
UsesUNC10217938A is a 3-deazapteridine analog with strong oligonucleotide enhancing effects. UNC10217938A enhances oligonucleotides effects by modulating their intracellular trafficking and release from endosomes. UNC10217938A also enhances the effects of antisense and siRNA oligonucleotides[1].
in vivo

Systemic treatment with SSO623 followed by administration of UNC10217938A (7.5 mg/kg; intravenous injection) produces distinct increases in EGFP fluorescence in liver, kidney and heart in EGFP654 mice[3].

References[1] Yang B, et al. High-throughput screening identifies small molecules that enhance the pharmacological effects of oligonucleotides. Nucleic Acids Res. 2015 Feb 27;43(4):1987-96. DOI:10.1093/nar/gkv060
ethyl 8-(2-(dimethylamino)ethylamino)-2,3-diphenylpyrido[2,3-b]pyrazin-6-ylcarbamate Preparation Products And Raw materials
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