UNC10217938A NEW
| Price | $1298 | $1939 | $2909 |
| Package | 25mg | 50mg | 100mg |
| Min. Order: | |
| Supply Ability: | 10g |
| Update Time: | 2025-08-21 |
Product Details
| Product Name: UNC10217938A | CAS No.: 1347749-97-6 |
| Supply Ability: 10g | Release date: 2025/08/21 |
Product Introduction
Bioactivity
| Name | UNC10217938A |
| Description | UNC10217938A is a 3-deazapteridine analog, has strong oligonucleotide enhancing effects. |
| In vitro | When UNC10217938A is used in the range of 5-25 μM, it can significantly enhance the induction of luciferase in HelaLuc705 cells, and it is more effective and more effective than Retro-1. Compared to a separate splice switch oligonucleotide (SSO), UNC10217938A provids a 60-fold enhancement at 10 μM and 220-fold at 20 μM, in contrast to a 11-fold enhancement for 100 μM Retro-1. UNC10217938A can substantially enhance effects of receptor targeted oligonucleotide conjugates. UNC10217938A can also enhance the effect of uncharged morpholino oligonucleotides and negatively charged oligonucleotides . Exposure of cells to UNC10217938A caused a significant reduction in the colocalization of TAMRA-oligonucleotides with the late ribosomal marker Rab7, but had little effect on the colocalization with the lysosomal marker LAMP-1. UNC10217938A causes partial release of oligonucleotide from late endosomes to the cytosol followed by nuclear accumulation. |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
| Keywords | UNC-10217938A | UNC10217938A |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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| Product name | Price | Suppliers | Update time | |
|---|---|---|---|---|
| $118.00/1mg |
VIP6Y
|
TargetMol Chemicals Inc.
|
2025-11-05 | |
| $1298.00/25mg |
VIP2Y
|
TargetMol Chemicals Inc.
|
2025-08-21 |
United States- Since: 2011-01-07
- Address: 36 Washington Street, Wellesley Hill, USA
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