UNC10217938A NEW
| Price | $1298 | $1939 | $2909 |
| Package | 25mg | 50mg | 100mg |
| Min. Order: | |
| Supply Ability: | 10g |
| Update Time: | 2025-08-22 |
Product Details
| Product Name: UNC10217938A | CAS No.: 1347749-97-6 |
| Supply Ability: 10g | Release date: 2025/08/22 |
Product Introduction
Bioactivity
| Name | UNC10217938A |
| Description | UNC10217938A is a 3-deazapteridine analog, has strong oligonucleotide enhancing effects. |
| In vitro | When UNC10217938A is used in the range of 5-25 μM, it can significantly enhance the induction of luciferase in HelaLuc705 cells, and it is more effective and more effective than Retro-1. Compared to a separate splice switch oligonucleotide (SSO), UNC10217938A provids a 60-fold enhancement at 10 μM and 220-fold at 20 μM, in contrast to a 11-fold enhancement for 100 μM Retro-1. UNC10217938A can substantially enhance effects of receptor targeted oligonucleotide conjugates. UNC10217938A can also enhance the effect of uncharged morpholino oligonucleotides and negatively charged oligonucleotides . Exposure of cells to UNC10217938A caused a significant reduction in the colocalization of TAMRA-oligonucleotides with the late ribosomal marker Rab7, but had little effect on the colocalization with the lysosomal marker LAMP-1. UNC10217938A causes partial release of oligonucleotide from late endosomes to the cytosol followed by nuclear accumulation. |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
| Keywords | UNC-10217938A | UNC10217938A |
Company Profile Introduction
TargetMol Chemicals Inc. is headquartered in Boston, MA, and specializes in products and services that serve the research needs of chemical and biological scientists worldwide. With a client base in 40+ countries, TargetMol has evolved into one of the biggest global research suppliers for compound libraries and small molecule compounds.
170+ Compound Libraries， 10000+ Noval Small Molecucles，16000+ Nature Compounds
TargetMol diligently updates and offers over 170 types of compound libraries and a wide range of high-quality research chemicals, including inhibitors, activators, natural products, peptides, antibodies , and novel life-science kits for laboratory and scientific use. In addition, our lab allows us to conduct CADD (computer-aided drug design) and chemical synthesis to meet the customization needs of our clients.
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United States- Since: 2011-01-07
- Address: 36 Washington Street, Wellesley Hill, Massachusetts, USA
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