Benzyl-PEG8-THP manufacturers
- Benzyl-PEG8-THP
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2025-06-07
- CAS:1611489-00-9
- Min. Order: 1g
- Purity: >98.00%
- Supply Ability: 1g
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| | Benzyl-PEG8-THP Basic information |
| Product Name: | Benzyl-PEG8-THP | | Synonyms: | Benzyl-PEG8-THP;Benzyl-PEG9-THP;Benzyl-PEG7-THP;CAS_1611489-00-9;2H-Pyran, tetrahydro-2-[(25-phenyl-3,6,9,12,15,18,21,24-octaoxapentacos-1-yl)oxy]-;2-((1-Phenyl-2,5,8,11,14,17,20,23-octaoxapentacosan-25-yl)oxy)tetrahydro-2H-pyran | | CAS: | 1611489-00-9 | | MF: | C28H48O10 | | MW: | 544.67 | | EINECS: | | | Product Categories: | | | Mol File: | 1611489-00-9.mol |  |
| | Benzyl-PEG8-THP Chemical Properties |
| Boiling point | 602.0±55.0 °C(Predicted) | | density | 1.11±0.1 g/cm3(Predicted) |
| | Benzyl-PEG8-THP Usage And Synthesis |
| Uses | Benzyl-PEG8-THP is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. | | Biological Activity | Benzyl-PEG8-THP is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. | | IC 50 | PEGs | | References | [1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 |
| | Benzyl-PEG8-THP Preparation Products And Raw materials |
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