Benzyl-PEG3-CH2CO2tBu manufacturers
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| | Benzyl-PEG3-CH2CO2tBu Basic information |
| Product Name: | Benzyl-PEG3-CH2CO2tBu | | Synonyms: | Benzyl-PEG3-CH2CO2tBu;Benzyl-PEG2-CH2-Boc;Acetic acid, 2-[2-[2-(phenylmethoxy)ethoxy]ethoxy]-, 1,1-dimethylethyl ester;tert-butyl 2-(2-(2-(benzyloxy)ethoxy)ethoxy)acetate | | CAS: | 1643957-26-9 | | MF: | C17H26O5 | | MW: | 310.39 | | EINECS: | | | Product Categories: | | | Mol File: | 1643957-26-9.mol |  |
| | Benzyl-PEG3-CH2CO2tBu Chemical Properties |
| storage temp. | Storage temp. 2-8°C | | form | Liquid | | color | Colorless to light yellow |
| | Benzyl-PEG3-CH2CO2tBu Usage And Synthesis |
| Description | Benzyl-PEG3-CH2CO2tBu is a PEG linker with a benzyl and t-butyl protecting group. Both protecting groups are acid labile. The hydrophilic PEG linker increases the water solubility of the compound in aqueous media. | | Uses | Benzyl-PEG2-CH2-Boc is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. | | References | [1] Ottis P, et al. Assessing Different E3 Ligases for Small Molecule Induced Protein Ubiquitination and Degradation. ACS Chem Biol. 2017 Oct 20;12(10):2570-2578. DOI:10.1021/acschembio.7b00485 |
| | Benzyl-PEG3-CH2CO2tBu Preparation Products And Raw materials |
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