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| | Hydroxy-PEG2-CH2CO2H Basic information |
| Product Name: | Hydroxy-PEG2-CH2CO2H | | Synonyms: | Hydroxy-PEG2-CH2CO2H, sodium salt;8-hydroxy-3,6-dioxaoctanoic acid;Hydroxy-PEG2-CH2CO2H;HO-PEG2-CH2COOH;OH-PEG2-CH2COOH;PEG2-CH2COOH;2-[2-(2-hydroxyethoxy)ethoxy]acetic acid;Acetic acid, 2-[2-(2-hydroxyethoxy)ethoxy]- | | CAS: | 51951-04-3 | | MF: | C6H12O5 | | MW: | 164.16 | | EINECS: | | | Product Categories: | peg | | Mol File: | 51951-04-3.mol |  |
| | Hydroxy-PEG2-CH2CO2H Chemical Properties |
| Boiling point | 343.4±22.0 °C(Predicted) | | density | 1.239±0.06 g/cm3(Predicted) | | storage temp. | Storage temp. 2-8°C | | solubility | Chloroform (Slightly), DMSO (Slightly) | | pka | 3.39±0.10(Predicted) | | form | Oil | | color | Colourless |
| | Hydroxy-PEG2-CH2CO2H Usage And Synthesis |
| Description | Hydroxy-PEG2-CH2CO2H sodium salt is a PEG linker containing a hydroxyl group with a terminal carboxylic acid (as sodium salt form). The free acid form is not stable due to the reaction of OH with PEG-COOH group to form polymer. The sodium salt form is stable for storage and shipping. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond. The hydrophilic PEG spacer increases solubility in aqueous media. The hydroxyl group enables further derivatization or replacement with other reactive functional groups. | | Uses | Hydroxy-PEG2-CH2CO2H can be used to prepare cyclin dependent kinase to treat cancer. | | IC 50 | PEGs |
| | Hydroxy-PEG2-CH2CO2H Preparation Products And Raw materials |
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