| Company Name: |
Alfa Chemistry |
| Tel: |
1-516-6625404 |
| Email: |
support@alfa-chemistry.com |
6,8-Difluoro-4-methyl-umbelliferyl phosphate manufacturers
- DiFMUP
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- $127.00
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2026-07-27
- CAS:214491-43-7
- Purity: 98.93%
- Supply Ability: 10g
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| | 6,8-Difluoro-4-methyl-umbelliferyl phosphate Basic information |
| Product Name: | 6,8-Difluoro-4-methyl-umbelliferyl phosphate | | Synonyms: | AURORA KA-6718;2H-1-Benzopyran-2-one, 6,8-difluoro-4-methyl-7-(phosphonooxy)-;DiFMU-Phos;6,8-Difluoro-4-methyl-2-oxo-2H-chromen-7-yl dihydrogen phosphate;DIFMUP;6,8-Difluoro-4-methyl-umbelliferyl phosphate | | CAS: | 214491-43-7 | | MF: | C10H7F2O6P | | MW: | 292.13 | | EINECS: | | | Product Categories: | | | Mol File: | 214491-43-7.mol |  |
| | 6,8-Difluoro-4-methyl-umbelliferyl phosphate Chemical Properties |
| Boiling point | 496.0±55.0 °C(Predicted) | | density | 1.716±0.06 g/cm3(Predicted) | | storage temp. | −20°C | | solubility | 29.21mg/ml in DMSO | | form | A solid | | pka | 1.48±0.10(Predicted) | | color | White to off-white | | Appearance | Solid Powder | | InChI | 1S/C10H7F2O6P/c1-4-2-7(13)17-9-5(4)3-6(11)10(8(9)12)18-19(14,15)16/h2-3H,1H3,(H2,14,15,16) | | InChIKey | DZANYXOTJVLAEE-UHFFFAOYSA-N | | SMILES | CC1=CC(=O)Oc2c(F)c(OP(O)(O)=O)c(F)cc12 |
| Safety Statements | 22-24/25 | | WGK Germany | WGK 3 | | Storage Class | 11 - Combustible Solids |
| | 6,8-Difluoro-4-methyl-umbelliferyl phosphate Usage And Synthesis |
| Description | 6,8-difluoro-4-methylumbelliferyl phosphate is a fluorogenic substrate for protein tyrosine phosphatase. | | Uses | DiFMUP is a fluorogenic substrate, and has been widely used for the continuous detection of phosphatase activities. DiFMUP is hydrolysis by a phosphatase results in the release of Xuorescent DIFMU, which can be easily followed in continuous mode by a Xuorescence reader[1][2]. | | Definition | ChEBI: 6,8-difluoro-4-methylumbelliferyl phosphate is a member of coumarins. It is functionally related to a coumarin. It is a conjugate acid of a 6,8-difluoro-4-methylumbelliferyl phosphate (2-). | | Biological Activity | DiFMUP (6,8-difluoro-4-methylumbelliferyl phosphate), a fluorinated analog of MUP, is a fluorescent synthetic substrate for continuous assessment of phosphatase activity. DiFMUP excitation/emission maxima are 358/450 nm. | | storage | Store at -20°C | | References | [1] Gee KR, et, al. Fluorogenic substrates based on fluorinated umbelliferones for continuous assays of phosphatases and beta-galactosidases. Anal Biochem. 1999 Aug 15;273(1):41-8. DOI:10.1006/abio.1999.4202
[2] Welte S, et, al. 6,8-Difluoro-4-methylumbiliferyl phosphate: a fluorogenic substrate for protein tyrosine phosphatases. Anal Biochem. 2005 Mar 1;338(1):32-8. DOI:10.1016/j.ab.2004.11.047 |
| | 6,8-Difluoro-4-methyl-umbelliferyl phosphate Preparation Products And Raw materials |
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