H-Ser-Tyr-Gly-Leu-Arg-Pro-Gly-NH2

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H-Ser-Tyr-Gly-Leu-Arg-Pro-Gly-NH2 Basic information
Product Name:H-Ser-Tyr-Gly-Leu-Arg-Pro-Gly-NH2
Synonyms:LUTEINIZING HORMONE RELEASING HORMONE FRAGMENT 4-10;LHRH (4-10);GONADOTROPIN-RELEASING HORMONE (4-10);luteinizing hormone releasing hormone*fragment 4-;lh-rh fragment 4-10;gonadotropin-releasing hormone I, fragment 4-10;LH-RH Fragment 4-10, Ser-Tyr-Gly-Leu-Arg-Pro-Gly-NH2;SER-TYR-GLY-LEU-ARG-PRO-GLY-NH2
CAS:51776-33-1
MF:C33H53N11O9
MW:747.84
EINECS:
Product Categories:
Mol File:51776-33-1.mol
H-Ser-Tyr-Gly-Leu-Arg-Pro-Gly-NH2 Structure
H-Ser-Tyr-Gly-Leu-Arg-Pro-Gly-NH2 Chemical Properties
density 1.48±0.1 g/cm3(Predicted)
storage temp. −20°C
pka9.82±0.15(Predicted)
Safety Information
Hazard Codes T
Risk Statements 60
Safety Statements 53-22-36/37/39-45
WGK Germany 3
MSDS Information
ProviderLanguage
SigmaAldrich English
H-Ser-Tyr-Gly-Leu-Arg-Pro-Gly-NH2 Usage And Synthesis
UsesLH-RH (4-10) is a heptapeptide, one of major degradation products of luteinising-hormone releasing hormone (LHRH) via pituitary and hypothalamus. LH-RH (4-10) produced in macrophages and type II pneumocytes[1].
References[1] Yang X, et al. Enzymatic degradation of luteinizing hormone releasing hormone (LHRH)/[D-Ala6]-LHRH in lung pneumocytes. Pharm Res. 1998 Sep;15(9):1480-4. DOI:10.1023/a:1011926310666
[2] Talwar GP, et al. Bioeffective monoclonal antibody against the decapeptide gonadotropin-releasing hormone: reacting determinant and action on ovulation and estrus suppression. Proc Natl Acad Sci U S A. 1985 Feb;82(4):1228-31. DOI:10.1073/pnas.82.4.1228
H-Ser-Tyr-Gly-Leu-Arg-Pro-Gly-NH2 Preparation Products And Raw materials
Preparation ProductsGonadorelin
Tag:H-Ser-Tyr-Gly-Leu-Arg-Pro-Gly-NH2(51776-33-1) Related Product Information
Gonadorelin acetate Gonadorelin Triptorelin Pyr-His-Trp-Ser-Tyr-D-Ala-Leu-Arg-Pro-Gly-NH2 (BIOTINYL-GLN1)-LHRH (DES-PYR1)-LHRH [D-Lys6]-LHRH (3,5-Diiodo-Tyr5)-lhrh Ac-(PCL)dphe-(PCL)dphe-dtrp-Ser-Tyr-darg-Leu-Arg-Pro-dala-NH2 Pglu-D-Phe-Trp-Ser-Tyr-D-Ala-Leu-Arg-Pro-Gly-NH2 D-Pyr-D-Phe-D-Trp-Ser-Tyr-D-Trp-Leu-Arg-Pro-Gly-NH2 pGlu-His-Trp-Ser-Tyr-Gly-Leu-Arg-Hyp-Gly-NH2 H-Ser-Tyr-Gly-Leu-Arg-Pro-Gly-NH2 Pyr-D-Phe-Pro-Ser-Tyr-D-Phe-Leu-Arg-Pro-Gly-NH2 H-Trp-Ser-Tyr-Gly-Leu-Arg-Pro-Gly-NH2 ([125I]-Tyr)-gonadorelin Gonadotrophin releasing hormone [pyroglutamyl-3,4-3H]- pGlu-His-Trp-Ser-Tyr-D-Ala-N-methyl-Leu-Arg-Pro-Gly-NH2