3-Mercaptopropionyl-beta-3-pyridyl-D-Ala-Phe-Gln-Asn-Cys-Pro-Arg-Gly-NH2

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3-Mercaptopropionyl-beta-3-pyridyl-D-Ala-Phe-Gln-Asn-Cys-Pro-Arg-Gly-NH2 Basic information
Product Name:3-Mercaptopropionyl-beta-3-pyridyl-D-Ala-Phe-Gln-Asn-Cys-Pro-Arg-Gly-NH2
Synonyms:D(D-3PAL)VP;(DEAMINO-CYS1,BETA-(3-PYRIDYL)-D-ALA2,ARG8)-VASOPRESSIN;[DEAMINO-CYS1,D-3-(PYRIDYL)-ALA2,ARG8]-VASOPRESSIN;(DEAMINO-CYS1,3-D-ALA(3'-PYRIDYL)ALA2,ARG8)-VASOPRESSIN;(deamino-cys1;(DEAMINO-CYS1, D-3-(PYRIDYL)ALA2, *ARG8) -VASOPRESSI;d3pvp;argipressin, 1-deamino-3-(3'-pyridyl)-Ala(2)-
CAS:136105-89-0
MF:C45H63N15O11S2
MW:1054.21
EINECS:
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Mol File:136105-89-0.mol
3-Mercaptopropionyl-beta-3-pyridyl-D-Ala-Phe-Gln-Asn-Cys-Pro-Arg-Gly-NH2 Structure
3-Mercaptopropionyl-beta-3-pyridyl-D-Ala-Phe-Gln-Asn-Cys-Pro-Arg-Gly-NH2 Chemical Properties
density 1.56±0.1 g/cm3(Predicted)
storage temp. −20°C
pka12.83±0.70(Predicted)
form Solid
Safety Information
Hazard Codes Xn
Risk Statements 20
Safety Statements 36
WGK Germany 3
MSDS Information
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SigmaAldrich English
3-Mercaptopropionyl-beta-3-pyridyl-D-Ala-Phe-Gln-Asn-Cys-Pro-Arg-Gly-NH2 Usage And Synthesis
UsesDesamino(D-3-(3′-pyridyl)-Ala2,Arg8)-Vasopressin, a synthetic analog of vasopressin (AVP), is a weak agonist at antidiuretic receptor. However, Desamino(D-3-(3′-pyridyl)-Ala2,Arg8)-Vasopressin is a potent agonist at pituitary corticotrope receptor[1].
in vivo

Desamino(D-3-(3′-pyridyl)-Ala2,Arg8)-Vasopressin (50 μg/sheep; i.v.; single dose) shows corticotropin-releasing activity in sheep[1].

References[1] Schwartz J, et al. A potent new synthetic analog of vasopressin with relative agonist specificity for the pituitary. Endocrinology. 1991 Aug;129(2):1107-9. DOI:10.1210/endo-129-2-1107
3-Mercaptopropionyl-beta-3-pyridyl-D-Ala-Phe-Gln-Asn-Cys-Pro-Arg-Gly-NH2 Preparation Products And Raw materials
Tag:3-Mercaptopropionyl-beta-3-pyridyl-D-Ala-Phe-Gln-Asn-Cys-Pro-Arg-Gly-NH2(136105-89-0) Related Product Information
3-Mercaptopropionyl-Tyr-Phe-Gln-Asn-Cys-Pro-Lys-Gly-NH2, (disulfide bond) (Deamino-Cys1,D-Orn8)-vasopressin (Deamino-Cys1,Val4,D-Arg8)-vasopressin (Deamino-Cys1,beta-cyclohexyl-Ala4,Arg8)-vasopressin D[LEU4,LYS8]-VP Desmopressin 3-Mercapto-3-methyl-butyryl-Tyr-Phe-Val-Asn-Cys-Pro-D-Arg-Gly-NH2 3-Mercapto-3-methyl-butyryl-Tyr(Me)-Phe-Gln-Asn-Cys-Pro-Arg-Gly-NH2 3-Pyridin-3-ylpropan-1-amine 3-Pyridineethaneamine (Arg8)-vasopressin (4-9) (2-Pyridin-3-ylethyl)methylamine 3-Mercaptopropionyl-beta-3-pyridyl-D-Ala-Phe-Gln-Asn-Cys-Pro-Arg-Gly-NH2 1-Methyl-2-pyridin-4-yl-ethylamine