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TYRPHOSTIN A63

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TYRPHOSTIN A63 Basic information
Product Name:TYRPHOSTIN A63
Synonyms:[4-HYDROXYBENZYL]MALONONITRILE;AG 43;ALPHA-CYANO-(4-HYDROXY)DIHYDROCINNAMONITRILE;RARECHEM AL BY 0097;TYRPHOSTIN AG 43;TYRPHOSTIN A63;TYRPHOSTIN 63;TYRPHOSTIN A63 99%
CAS:5553-97-9
MF:C10H8N2O
MW:172.18
EINECS:
Product Categories:
Mol File:5553-97-9.mol
TYRPHOSTIN A63 Structure
TYRPHOSTIN A63 Chemical Properties
storage temp. 2-8°C
Safety Information
WGK Germany 3
MSDS Information
ProviderLanguage
SigmaAldrich English
TYRPHOSTIN A63 Usage And Synthesis
UsesTyrphostin 63 (compound 13) is an epidermal growth factor receptor (EGFR) inhibitor with IC50 and Ki values are 375 and 123 μM, respectively[1].
DefinitionChEBI: 2-[(4-hydroxyphenyl)methyl]propanedinitrile is a member of phenols.
References[1] Gazit A, et al. Tyrphostins I: synthesis and biological activity of protein tyrosine kinase inhibitors. J Med Chem. 1989 Oct;32(10):2344-52. DOI:10.1021/jm00130a020
TYRPHOSTIN A63 Preparation Products And Raw materials
Tag:TYRPHOSTIN A63(5553-97-9) Related Product Information
TYRPHOSTIN A51 TYRPHOSTIN AG 126 TYRPHOSTIN AG 1288 TYRPHOSTIN A9 TYRPHOSTIN A25 2-(4-Methoxyphenyl)-6,6-dimethyl-4,8-dioxospiro[2.5]octane-1,1-dicarbonitrile AG 213 NS-398 SALOR-INT L153680-1EA QUINOLIN DERIVATIVE DIMETHYL 5,5-DICYANO-4-(4-ETHOXYPHENYL)-2-HYDROXY-6-(4-METHYLPHENYL)-1-CYCLOHEXENE-1,3-DICARBOXYLATE DIMETHYL 5,5-DICYANO-6-(4-CYANOPHENYL)-4-(4-ETHOXYPHENYL)-2-HYDROXY-1-CYCLOHEXENE-1,3-DICARBOXYLATE 2-(4-METHOXYBENZYL)MALONONITRILE TYRPHOSTIN A63