| Company Name: |
BOC Sciences |
| Tel: |
16314854226; +8616314854226 |
| Email: |
inquiry@bocsci.com |
CAY10717 manufacturers
- CAY10717
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- $159.00
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2026-07-27
- CAS:1240322-54-6
- Purity:
- Supply Ability: 10g
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| | CAY10717 Basic information |
| Product Name: | CAY10717 | | Synonyms: | CAY10717;CAY-10717,CAY10717;1H-Pyrrolo[2,3-b]pyridine-2-carboxylic acid, 5-[[[2-methyl-5-[[3-(4-methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)benzoyl]amino]phenyl]methyl]amino]-, methyl ester;5-[[[2-methyl-5-[[3-(4-methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)benzoyl]amino]phenyl]methyl]amino]-1H-pyrrolo[2,3-b]pyridine-2-carboxylicacid,methylester | | CAS: | 1240322-54-6 | | MF: | C29H25F3N6O3 | | MW: | 562.54 | | EINECS: | | | Product Categories: | | | Mol File: | 1240322-54-6.mol |  |
| | CAY10717 Chemical Properties |
| density | 1.39±0.1 g/cm3(Predicted) | | storage temp. | Store at -20°C | | solubility | DMF: 30 mg/ml; DMF:PBS(pH7.2) (1:2): 0.33 mg/ml; DMSO: 12.5 mg/ml; Ethanol: 0.5 mg/ml | | form | A crystalline solid | | pka | 12.14±0.40(Predicted) |
| | CAY10717 Usage And Synthesis |
| Description | CAY10717 is a multi-targeted kinase inhibitor | | Uses | Antiproliferative agent-54 (Compound 6z) is the inhibitor for multiple kinases, such as ABL WT, B-RAF, EGFR, HCK, LYN A and SRC with IC50 of 6-50 nM. Antiproliferative agent-54 inhibits proliferation of several cancer cell, inhibits HUVEC and HepG2, with EC50 of 34 and 38 nM. Antiproliferative agent-54 exhibits good pharmacokinetic characteristics in rats[1]. | | References | [1] Daydé-Cazals B, et al., Rational Design, Synthesis, and Biological Evaluation of 7-Azaindole Derivatives as Potent Focused Multi-Targeted Kinase Inhibitors. J Med Chem. 2016 Apr 28;59(8):3886-905. DOI:10.1021/acs.jmedchem.6b00087 |
| | CAY10717 Preparation Products And Raw materials |
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